Hydrochloric Acid

Hydrochloric Acid

SCHEMBL4377339

CCCCC[n+]1cc[nH]c1C.[Cl-]

nearest known ligand 0.41

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Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 known ✓ P08172 2/20 0.35
CHRM1 known ✓ P11229 2/20 0.35
ACHE known ✓ P22303 2/20 0.35
SLC6A2 known ✓ P23975 2/20 0.35
SLC6A3 known ✓ Q01959 2/20 0.35
CHRM3 known ✓ P20309 1/20 0.34
HTT P42858 4/20 0.41
KMT2A Q03164 4/20 0.38
SMN1; SMN2 Q16637 4/20 0.38
MEN1 O00255 3/20 0.38
MAPT P10636 2/20 0.38
MAPK1 P28482 2/20 0.38
CASP2 P42575 1/20 0.38
TP53 P04637 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5173929 0.98 HTT (0.44) HTTKMT2ASMN1; SMN2MEN1MAPT
Hydrochloric Acid SCHEMBL5173901 0.98 HTT (0.44) HTTKMT2ASMN1; SMN2MEN1MAPT
Hydrochloric Acid SCHEMBL4227151 0.98 HTT (0.44) HTTKMT2ASMN1; SMN2MEN1MAPT
Hydrochloric Acid SCHEMBL5175241 0.98 HTT (0.44) HTTKMT2ASMN1; SMN2MEN1MAPT
Hydrochloric Acid SCHEMBL2935144 0.98 HTT (0.44) HTTKMT2ASMN1; SMN2MEN1MAPT
Hydrochloric Acid SCHEMBL126421 0.98 HTT (0.44) HTTKMT2ASMN1; SMN2MEN1MAPT
Hydrochloric Acid SCHEMBL5172897 0.98 HTT (0.44) HTTKMT2ASMN1; SMN2MEN1MAPT
SCHEMBL3742673 0.98 HTT (0.42) HTTKMT2ASMN1; SMN2MEN1MAPT
Iodide SCHEMBL6010405 0.96 HTT (0.41) HTTKMT2ASMN1; SMN2MEN1MAPT
SCHEMBL363480 0.96 HTT (0.46) HTTKMT2ASMN1; SMN2MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009102419-A2 ALUMINUM RECOVERY PROCESS THE UNIVERSITY OF ALABAMA (US) 2009-08-20 WO claimed