Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | BRD2 | P25440 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9434905 | 0.88 | BRD4 (0.43) | BRD4BRD2PIK3CDLMNACA12 | |
| SCHEMBL26805306 | 0.79 | PIK3CD (0.44) | BRD4BRD2PIK3CDLMNACA12 | |
| SCHEMBL5230712 | 0.75 | BRD4 (0.35) | BRD4BRD2PIK3CDTP53LMNA | |
| SCHEMBL20909425 | 0.75 | BRD4 (0.41) | BRD4BRD2PIK3CDLMNACA12 | |
| SCHEMBL6645160 | 0.73 | BRD4 (0.40) | BRD4BRD2PIK3CDLMNACA12 | |
| SCHEMBL5668991 | 0.73 | TSHR (0.36) | BRD4BRD2PIK3CDLMNACA12 | |
| SCHEMBL9989649 | 0.73 | LMNA (0.37) | BRD4BRD2PIK3CDTP53LMNA | |
| SCHEMBL9723828 | 0.73 | GAA (0.38) | ALOX5 | |
| SCHEMBL6047009 | 0.69 | — | — | |
| SCHEMBL9381608 | 0.68 | SLC6A2 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9994560-B2 | HPTP-β inhibitors | AERPIO THERAPEUTICS, INC. (US) | 2018-06-12 | — | — | US | disclosed |