Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | BRD2 | P25440 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11242674 | 0.76 | LMNA (0.40) | LMNACA12CA1CA2CA3 | |
| SCHEMBL16908564 | 0.76 | KDM4E (0.32) | ALDH1A1RAB9A | |
| SCHEMBL20243443 | 0.73 | BRD4 (0.38) | LMNACA12CA1CA2CA3 | |
| SCHEMBL11245719 | 0.72 | LMNA (0.37) | LMNACA12CA1CA2CA3 | |
| SCHEMBL5230712 | 0.70 | BRD4 (0.35) | LMNACA12CA1CA2CA3 | |
| SCHEMBL9587421 | 0.70 | LMNA (0.38) | LMNACA12CA1CA2CA3 | |
| SCHEMBL9628933 | 0.68 | TSHR (0.45) | LMNACA12CA1CA2CA3 | |
| SCHEMBL9434905 | 0.67 | BRD4 (0.43) | LMNACA12CA1CA2CA3 | |
| SCHEMBL15998842 | 0.67 | KMT2A (0.47) | TSHRKMT2APIK3CDALDH1A1RAB9A | |
| SCHEMBL11513318 | 0.66 | ALDH1A1 (0.40) | CYP1A2KMT2AUSP2L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011161615-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2011-12-29 | — | — | WO | claimed |