Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10864393 | 0.84 | FAAH (0.36) | GAAALOX5MC4RFAAHMGLL | |
| SCHEMBL11742720 | 0.75 | GAA (0.36) | GAAMC4RL3MBTL1MEN1KMT2A | |
| SCHEMBL20243443 | 0.73 | BRD4 (0.38) | ALOX5 | |
| Undecane SCHEMBL28268300 | 0.72 | BRD4 (0.61) | GAAALOX5FAAHMGLLL3MBTL1 | |
| SCHEMBL10816721 | 0.71 | ALOX5 (0.46) | GAAALOX5FAAHMGLLL3MBTL1 | |
| SCHEMBL8967917 | 0.71 | ALOX5 (0.46) | GAAALOX5FAAHMGLLL3MBTL1 | |
| SCHEMBL5858660 | 0.71 | ALOX5 (0.46) | GAAALOX5FAAHMGLLL3MBTL1 | |
| SCHEMBL11847945 | 0.71 | ALOX5 (0.46) | GAAALOX5FAAHMGLLL3MBTL1 | |
| SCHEMBL11851404 | 0.71 | ALOX5 (0.46) | GAAALOX5FAAHMGLLL3MBTL1 | |
| SCHEMBL10481688 | 0.71 | ALOX5 (0.46) | GAAALOX5FAAHMGLLL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0368933-B1 | COMPOSITIONS COMPRISING 1-OXO- OR THIOHYDROCARBYL SUBSTITUTED AZACYCLOALKANES | Whitby Research Incorporated (US) | 1992-10-14 | — | — | EP | disclosed |
| EP-0368933-A1 | COMPOSITIONS COMPRISING 1-OXO- OR THIOHYDROCARBYL SUBSTITUTED AZACYCLOALKANES | Whitby Research Incorporated (US) | 1990-05-23 | — | — | EP | disclosed |
| US-4920101-A | FOR ENHANCING PENETRATION OF PHYSIOLOGICALLY ACTIVE AGENTS THROUGH SKIN OR OTHER MEMBRANES | NELSON RESEARCH & DEVELOPMENT CO. (US) | 1990-04-24 | — | — | US | disclosed |
| EP-0368933-A4 | COMPOSITIONS COMPRISING 1-OXO- OR THIOHYDROCARBYL SUBSTITUTED AZACYCLOALKANES. | WHITBY RES INC (US) | 1990-03-28 | — | — | EP | disclosed |
| WO-1989002735-A1 | COMPOSITIONS COMPRISING 1-OXO- OR THIOHYDROCARBYL SUBSTITUTED AZACYCLOALKANES | NELSON RESEARCH & DEVELOPMENT CO. (US) | 1989-04-06 | — | — | WO | disclosed |