Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FHIT | P49789 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | GLA | P06280 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | CASP1 | P29466 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | CASP7 | P55210 | 1/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 6/20 | 0.56 |
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4710609 | 0.88 | FHIT (0.71) | FHITKDM4EALDH1A1HSD17B10KMT2A | |
| SCHEMBL4710697 | 0.82 | FHIT (0.76) | FHITKDM4EALDH1A1HSD17B10KMT2A | |
| SCHEMBL4711017 | 0.81 | KDM4E (0.95) | FHITKDM4EALDH1A1HSD17B10KMT2A | |
| SCHEMBL4709622 | 0.80 | KDM4E (0.67) | FHITKDM4EALDH1A1HSD17B10KMT2A | |
| SCHEMBL4712030 | 0.79 | KDM4E (0.77) | FHITKDM4EALDH1A1HSD17B10KMT2A | |
| SCHEMBL4708976 | 0.79 | KDM4E (0.70) | FHITKDM4EALDH1A1HSD17B10KMT2A | |
| SCHEMBL4709413 | 0.78 | KDM4E (0.68) | FHITKDM4EALDH1A1HSD17B10KMT2A | |
| SCHEMBL4710927 | 0.78 | FHIT (0.70) | FHITKDM4EALDH1A1HSD17B10KMT2A | |
| SCHEMBL4708929 | 0.77 | FHIT (0.69) | FHITKDM4EALDH1A1HSD17B10KMT2A | |
| SCHEMBL4712732 | 0.77 | ALDH1A1 (0.70) | FHITKDM4EALDH1A1HSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2892525-B1 | METHODS OF TREATING MUSCULAR DYSTROPHY | UNIV NEVADA RENO (US) | 2018-06-13 | — | — | EP | disclosed |