Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.39 |
| ▸ | CD38 | P28907 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL560745 | 0.76 | LMNA (0.55) | KMT2AMEN1ADRA2AADRA2BADRA2C | |
| SCHEMBL5477 | 0.75 | ADRA2A (0.71) | KMT2AADRA2AADRA2BADRA2CLMNA | |
| SCHEMBL1178134 | 0.73 | MAPT (0.48) | KMT2AALDH1A1MEN1HSD17B10MAPT | |
| SCHEMBL1179567 | 0.73 | CFB (0.39) | ADRA2AADRA2BADRA2CP2RX7CD38 | |
| SCHEMBL14381010 | 0.72 | ALDH1A1 (0.51) | KMT2AALDH1A1MEN1ADRA2AADRA2B | |
| SCHEMBL11182854 | 0.72 | KMT2A (0.45) | KMT2AALDH1A1MEN1ADRA2AADRA2B | |
| SCHEMBL11166542 | 0.71 | ALDH1A1 (0.52) | KMT2AALDH1A1MEN1ADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL11177608 | 0.70 | ALDH1A1 (0.51) | KMT2AALDH1A1MEN1ADRA2AADRA2B | |
| SCHEMBL5586 | 0.68 | ADRA2A (0.67) | KMT2AMEN1ADRA2AADRA2BADRA2C | |
| SCHEMBL13886573 | 0.68 | SLC6A2 (0.47) | ALDH1A1HTTP2RX7CD38 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3332782-A1 | METHOD OF ACTIVATING REGULATORY T CELLS WITH ALPHA-2B ADRENERGIC RECEPTOR AGONISTS | ALLERGAN, INC. (US) | 2018-06-13 | — | — | EP | disclosed |