Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 4/20 | 0.65 |
| ▸ | BRD4 | O60885 | 1/20 | 0.53 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.52 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.52 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.52 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.52 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.52 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.52 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.52 |
| ▸ | DDO | Q99489 | 3/20 | 0.51 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20247282 | 0.83 | DAO (0.71) | DAOBRD4GRIN2DGRIN3BGRIN1 | |
| SCHEMBL30667289 | 0.83 | DAO (0.71) | DAOBRD4GRIN2DGRIN3BGRIN1 | |
| SCHEMBL22571313 | 0.79 | DAO (0.61) | DAOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL16767849 | 0.79 | DAO (1.00) | DAOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL31139816 | 0.79 | DAO (0.65) | DAOBRD4GRIN2DGRIN3BGRIN1 | |
| SCHEMBL29471220 | 0.79 | BRD4 (0.53) | DAOBRD4GRIN2DGRIN3BGRIN1 | |
| SCHEMBL26551030 | 0.79 | BRD4 (0.53) | DAOBRD4GRIN2DGRIN3BGRIN1 | |
| SCHEMBL12970533 | 0.79 | DAO (0.65) | DAOBRD4GRIN2DGRIN3BGRIN1 | |
| SCHEMBL20940121 | 0.78 | DAO (0.59) | DAOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL30716611 | 0.78 | DAO (0.59) | DAOGRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11753400-B2 | D-amino acid oxidase inhibitors and therapeutic uses thereof | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2023-09-12 | — | — | US | disclosed |
| WO-2019076329-A9 | D-AMINO ACID OXIDASE INHIBITORS AND THERAPEUTIC USES THEREOF | TSAI GUOCHUAN EMIL (CN) | 2019-08-15 | — | — | WO | disclosed |
| WO-2019076329-A1 | D-AMINO ACID OXIDASE INHIBITORS AND THERAPEUTIC USES THEREOF | TSAI GUOCHUAN EMIL (CN) | 2019-04-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11753400-B2 | D-amino acid oxidase inhibitors and therapeutic uses thereof | DAO, DDO, DDC | DAO 1/4885BRD4 3000/4885GRIN2D 173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.