Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18357966 | 0.80 | PDK2 (0.36) | MAPK1PDPK1 | |
| SCHEMBL3954043 | 0.77 | MAPK1 (0.44) | MAPK1PDPK1 | |
| SCHEMBL12467739 | 0.77 | DYRK1A (0.37) | MAPK1PDPK1 | |
| SCHEMBL23962575 | 0.74 | KDM4E (0.39) | MAPK1PDPK1 | |
| SCHEMBL3950985 | 0.73 | PDPK1 (0.38) | MAPK1PDPK1 | |
| SCHEMBL19260963 | 0.72 | JAK2 (0.43) | MAPK1 | |
| SCHEMBL23169547 | 0.69 | ALDH1A1 (0.37) | MAPK1PDPK1 | |
| SCHEMBL24121831 | 0.69 | YTHDC1 (0.33) | — | |
| SCHEMBL24121832 | 0.68 | PDPK1 (0.35) | MAPK1PDPK1 | |
| SCHEMBL23229339 | 0.68 | DYRK1A (0.36) | PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021254493-A1 | CYCLIC COMPOUND HAVING ANTI-TUMOR ACTIVITY AND USE THEREOF | 上海翊石医药科技有限公司 | 2021-12-23 | — | — | WO | disclosed |
| EP-3333157-B1 | VINYL COMPOUNDS AS FGFR AND VEGFR INHIBITORS | HARBIN ZHENBAO PHARMACEUTICAL CO LTD (CN) | 2020-12-23 | — | — | EP | disclosed |
| EP-3333157-A1 | VINYL COMPOUNDS AS FGFR AND VEGFR INHIBITORS | Harbin Zhenbao Pharmaceutical Co., Ltd. (CN) | 2018-06-13 | — | — | EP | disclosed |