Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2028007 | 0.78 | PPARG (0.54) | MAPK1ALDH1A1SMN1; SMN2PKMLMNA | |
| SCHEMBL2024185 | 0.75 | MAPK1 (0.46) | ADAM17POLBMAPK1L3MBTL1KDM4E | |
| SCHEMBL6378155 | 0.70 | POLB (0.36) | POLBMAPK1L3MBTL1ALDH1A1GAA | |
| SCHEMBL20886627 | 0.69 | HTT (0.71) | POLBMAPK1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6211886 | 0.69 | CTSK (0.67) | — | |
| SCHEMBL1931269 | 0.68 | HTT (0.71) | POLBL3MBTL1KDM4EALDH1A1GAA | |
| SCHEMBL9099120 | 0.68 | HTT (0.71) | POLBL3MBTL1KDM4EALDH1A1GAA | |
| SCHEMBL8659778 | 0.68 | POLB (0.46) | ADAM17POLBMAPK1L3MBTL1KDM4E | |
| SCHEMBL9422948 | 0.67 | POLB (0.45) | POLBMAPK1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL2029510 | 0.67 | HSD11B1 (0.45) | ADAM17ALDH1A1GAALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110152480-A1 | Catalysts for Polymerizing Olefins and Method Thereof | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2011-06-23 | — | — | US | disclosed |
| US-20110152480-A1 | Catalysts for Polymerizing Olefins and Method Thereof | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2011-06-23 | — | — | US | disclosed |
| US-20110152480-A1 | Catalysts for Polymerizing Olefins and Method Thereof | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2011-06-23 | — | — | US | disclosed |
| EP-2331589-A1 | CATALYSTS FOR POLYMERIZING OLEFINS AND METHOD THEREOF | Basell Poliolefine Italia S.R.L. (IT) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010026184-A1 | CATALYSTS FOR POLYMERIZING OLEFINS AND METHOD THEREOF | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2010-03-11 | — | — | WO | disclosed |
| WO-2010026184-A1 | CATALYSTS FOR POLYMERIZING OLEFINS AND METHOD THEREOF | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2010-03-11 | — | — | WO | disclosed |