Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9427630 | 0.80 | LMNA (0.42) | POLBMAPK1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL28617660 | 0.80 | ALDH1A1 (0.43) | POLBMAPK1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL465266 | 0.79 | LMNA (0.41) | POLBMAPK1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL10767133 | 0.77 | TSHR (0.52) | POLBLMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL8896301 | 0.76 | L3MBTL1 (0.42) | POLBMAPK1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL42561 | 0.75 | LMNA (0.38) | POLBMAPK1LMNAL3MBTL1SMN1; SMN2 | |
| SCHEMBL2392777 | 0.75 | ELANE (0.41) | LMNAL3MBTL1SMN1; SMN2GAAKDM4E | |
| SCHEMBL4753583 | 0.73 | ALDH1A1 (0.47) | POLBLMNASMN1; SMN2GAAKDM4E | |
| SCHEMBL2609246 | 0.73 | HCAR2 (0.54) | L3MBTL1SMN1; SMN2KDM4EALDH1A1ELANE | |
| SCHEMBL585750 | 0.73 | HCAR2 (0.54) | L3MBTL1SMN1; SMN2KDM4EALDH1A1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354549-A | Iodinated esters | NYCOMED IMAGING AS (NO) | 1994-10-11 | — | — | US | disclosed |
| EP-0300828-B1 | IODINATED ESTERS | NYCOMED AS (NO) | 1992-03-18 | — | — | EP | disclosed |
| WO-1989000988-A1 | IODINATED ESTERS | NYCOMED AS (NO) | 1989-02-09 | — | — | WO | disclosed |
| EP-0300828-A1 | Iodinated esters | NYCOMED AS (NO) | 1989-01-25 | — | — | EP | disclosed |