SCHEMBL202491

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL201488	0.92	NPC1 (0.43)	PCSK9NPC1RAB9AEPHX2MAPT
	SCHEMBL204150	0.88	NPC1 (0.46)	NPC1RAB9AEPHX2MAPTSMN1; SMN2
	SCHEMBL202801	0.87	NPC1 (0.47)	NPC1RAB9AEPHX2MAPTSMN1; SMN2
	SCHEMBL14421920	0.86	NPC1 (0.47)	NPC1RAB9AMAPTSMN1; SMN2MAOB
	SCHEMBL2707355	0.86	NPC1 (0.38)	PCSK9NPC1RAB9AEPHX2MAPT
	SCHEMBL201760	0.84	HSD17B1 (0.45)	NPC1RAB9AMAPTSMN1; SMN2PKM
	SCHEMBL204718	0.83	NPC1 (0.37)	PCSK9NPC1RAB9AEPHX2MAPT
	SCHEMBL16872743	0.83	NPC1 (0.45)	NPC1RAB9AEPHX2MAPTSMN1; SMN2
	SCHEMBL2707368	0.83	SMN1; SMN2 (0.47)	NPC1RAB9AMAPTSMN1; SMN2GAA
	SCHEMBL2707199	0.82	NPC1 (0.46)	NPC1RAB9AEPHX2MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.