SCHEMBL2707368

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2707321	0.92	NPC1 (0.43)	SMN1; SMN2MEN1TNFLMNAGAA
	SCHEMBL16872743	0.89	NPC1 (0.45)	SMN1; SMN2LMNAGAAMAPTHPGD
	SCHEMBL201760	0.86	HSD17B1 (0.45)	SMN1; SMN2MEN1LMNAGAAMAPT
	SCHEMBL204150	0.86	NPC1 (0.46)	SMN1; SMN2MEN1MAPTHPGDKMT2A
	SCHEMBL14421920	0.86	NPC1 (0.47)	SMN1; SMN2GAAMAPTHPGDHTT
	SCHEMBL202801	0.85	NPC1 (0.47)	SMN1; SMN2MAPTHPGDNPC1RAB9A
	SCHEMBL204428	0.83	NPC1 (0.46)	SMN1; SMN2LMNAGAACYP3A4NPC1
	SCHEMBL202491	0.83	PCSK9 (0.43)	SMN1; SMN2MEN1GAAMAPTHPGD
	SCHEMBL204282	0.81	NPC1 (0.64)	SMN1; SMN2MEN1MAPTHPGDKMT2A
	SCHEMBL2704604	0.80	NPC1 (0.44)	SMN1; SMN2MAPTALDH1A1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.