Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KIF11 | P52732 | 4/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29328851 | 0.83 | MEN1 (0.48) | MEN1KMT2AKIF11EPHX2TGM2 | |
| SCHEMBL20249819 | 0.82 | MEN1 (0.67) | MEN1KMT2AKIF11IDO1NPSR1 | |
| SCHEMBL19192553 | 0.80 | RAB9A (0.49) | MEN1KMT2AIDO1TGM2CA1 | |
| SCHEMBL19492784 | 0.76 | NPC1 (0.53) | MEN1KMT2AIDO1CA1CA2 | |
| SCHEMBL6437577 | 0.72 | KIF11 (0.59) | KIF11EPHX2IDO1TGM2CA1 | |
| SCHEMBL5543119 | 0.72 | TGM2 (0.46) | KIF11EPHX2TGM2CA1CA2 | |
| SCHEMBL5543113 | 0.72 | TGM2 (0.46) | KIF11EPHX2TGM2CA1CA2 | |
| Hydrochloric Acid SCHEMBL11253689 | 0.71 | KIF11 (0.58) | KIF11EPHX2IDO1TGM2CA1 | |
| SCHEMBL19492694 | 0.70 | MAPT (0.46) | MEN1KMT2AEPHX2IDO1CA2 | |
| SCHEMBL20250034 | 0.70 | NPC1 (0.59) | MEN1KMT2ACA2NPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018107056-A1 | 1,3-SUBSTITUED PYRAZOLE COMPOUNDS USEFUL FOR REDUCTION OF VERY LONG CHAIN FATTY ACIC LEVELS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2018-06-14 | — | — | WO | disclosed |