Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ACP3 | P15309 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | MME | P08473 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL809548 | 0.77 | LMNA (0.37) | ALDH1A1L3MBTL1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL9401364 | 0.74 | CTSA (0.41) | ESR1 | |
| SCHEMBL28292778 | 0.73 | ESR1 (0.43) | ESR1ACP3ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL28378508 | 0.70 | ESR1 (0.41) | ESR1ACP3ALDH1A1TSHRMME | |
| SCHEMBL6546306 | 0.70 | ESR1 (0.56) | ESR1ACP3ALDH1A1TSHRADRA2A | |
| SCHEMBL2550047 | 0.69 | ESR1 (0.46) | ESR1ACP3ALDH1A1TSHRADRA2A | |
| SCHEMBL9165865 | 0.69 | ESR1 (0.46) | ESR1ACP3ALDH1A1TSHRADRA2A | |
| SCHEMBL809567 | 0.69 | LMNA (0.39) | ALDH1A1L3MBTL1SMN1; SMN2LMNAKDM4E | |
| SCHEMBL15141737 | 0.68 | ALDH1A1 (0.41) | ACP3ALDH1A1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL28405616 | 0.67 | ESR1 (0.41) | ESR1ACP3ALDH1A1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2331589-A1 | CATALYSTS FOR POLYMERIZING OLEFINS AND METHOD THEREOF | Basell Poliolefine Italia S.R.L. (IT) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010026184-A1 | CATALYSTS FOR POLYMERIZING OLEFINS AND METHOD THEREOF | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2010-03-11 | — | — | WO | disclosed |