SCHEMBL809567

SCHEMBL809567

CC(C=O)Sc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
L3MBTL1 Q9Y468 3/20 0.39
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
KDM4E B2RXH2 3/20 0.37
GAA P10253 3/20 0.37
ALDH1A1 P00352 2/20 0.37
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36
MGLL Q99685 1/20 0.36
HSD17B10 Q99714 1/20 0.36
PKM P14618 1/20 0.36
POLB P06746 2/20 0.35
MAPK1 P28482 1/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
TAAR1 Q96RJ0 1/20 0.34
MTNR1A P48039 3/20 0.34
MTNR1B P49286 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1453422 0.79 MAOA (0.39) LMNASMN1; SMN2L3MBTL1MAOAMAOB
SCHEMBL11292783 0.78 HSD17B10 (0.47) LMNASMN1; SMN2L3MBTL1MAPTHPGD
SCHEMBL10402880 0.78 MEN1 (0.41) LMNASMN1; SMN2L3MBTL1MAOAMAOB
SCHEMBL809548 0.78 LMNA (0.37) LMNASMN1; SMN2L3MBTL1MAOAMAOB
SCHEMBL10404224 0.77 MAOA (0.38) LMNASMN1; SMN2L3MBTL1MAOAMAOB
SCHEMBL28694462 0.77 MAOA (0.38) LMNASMN1; SMN2L3MBTL1MAOAMAOB
SCHEMBL11291833 0.75 MGLL (0.36) LMNASMN1; SMN2L3MBTL1MAOAKDM4E
SCHEMBL10403945 0.74 SMN1; SMN2 (0.49) LMNASMN1; SMN2L3MBTL1KDM4EGAA
SCHEMBL10589164 0.74 CES2 (0.35) ALDH1A1SLC6A4
SCHEMBL95521 0.73 LMNA (0.42) LMNASMN1; SMN2L3MBTL1MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117897423-A Stabilized poly (alkylaldehydes) 博伊西州立大学 2024-04-16 CN claimed
CN-117897423-A Stabilized poly (alkylaldehydes) 博伊西州立大学 2024-04-16 CN disclosed
US-7968734-B2 Organocatalysts and methods of use in chemical synthesis STC.UNM (US) 2011-06-28 US disclosed
US-20070244328-A1 Organocatalysts and Methods of Use in Chemical Synthesis STC.UNM (US) 2007-10-18 US disclosed
US-4914206-A ANTIBIOTICS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1990-04-03 US disclosed
EP-0244195-A1 2-Vinylpenams and process THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD (GB) 1987-11-04 EP disclosed
EP-0226896-A2 Lankacidin derivatives and production thereof Takeda Chemical Industries, Ltd. (JP) 1987-07-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070244328-A1 Organocatalysts and Methods of Use in Chemical Synthesis SCO2, CBR1, CBR3 LMNA 924/4885SMN1; SMN2 3982/4885L3MBTL1 3514/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.