Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28337714 | 0.82 | NFE2L2 (0.50) | NFE2L2CYP1A1CYP1B1CYP1A2RELA | |
| SCHEMBL5442396 | 0.80 | NFE2L2 (0.49) | NFE2L2CYP1A1CYP1B1CYP1A2RELA | |
| SCHEMBL16958554 | 0.80 | NFE2L2 (0.49) | NFE2L2CYP1A1CYP1B1CYP1A2RELA | |
| SCHEMBL387186 | 0.80 | ERN1 (0.61) | NFE2L2CYP1A1CYP1B1CYP1A2RELA | |
| SCHEMBL7483621 | 0.77 | NFE2L2 (0.54) | NFE2L2CYP1A1CYP1B1CYP1A2RELA | |
| SCHEMBL7483615 | 0.77 | NFE2L2 (0.54) | NFE2L2CYP1A1CYP1B1CYP1A2RELA | |
| SCHEMBL12820112 | 0.76 | ERN1 (0.67) | CYP1A1CYP1B1CYP1A2RELAERN1 | |
| SCHEMBL20961911 | 0.76 | ALDH1A1 (0.52) | NFE2L2CYP1A1CYP1B1CYP1A2ERN1 | |
| SCHEMBL18490047 | 0.76 | KMT2A (0.54) | NFE2L2CYP1A1CYP1B1CYP1A2RELA | |
| SCHEMBL5764749 | 0.76 | KMT2A (0.54) | NFE2L2CYP1A1CYP1B1CYP1A2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018106284-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2018-06-14 | — | — | WO | disclosed |