SCHEMBL202570

SCHEMBL202570

N#CCCn1nc(-c2ccc(OCc3ccccc3)cc2)oc1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7297318 0.83 MAOB (0.71) MAOB
SCHEMBL9424210 0.72 MAOB (0.57) MAOB
SCHEMBL14527001 0.72 MAOB (1.00) MAOB
SCHEMBL9638028 0.72 MAOB (0.70) MAOB
SCHEMBL7297313 0.72 MAOB (0.56) MAOB
SCHEMBL27740555 0.70 MAOB (0.56) MAOB
SCHEMBL29032391 0.69 KDM4E (0.64) MAOB
SCHEMBL2617467 0.68 FAAH (0.55) MAOB
SCHEMBL27037987 0.68 MAOB (0.66) MAOB
SCHEMBL9462380 0.67 MAOB (0.59) MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260092038-A1 CANNABINOID RECEPTOR 1 ANTAGONISTS/INVERSE AGONISTS AND USES THEREOF CORBUS PHARMACEUTICALS INC (US) 2026-04-02 US disclosed
US-20250248973-A1 CANNABINOID RECEPTOR 1 ANTAGONISTS/INVERSE AGONISTS AND USES THEREOF CORBUS PHARMACEUTICALS, INC. 2025-08-07 US disclosed
EP-4504179-A1 CANNABINOID RECEPTOR 1 ANTAGONISTS/INVERSE AGONISTS AND USES THEREOF Corbus Pharmaceuticals, Inc. (US) 2025-02-12 EP disclosed
CN-119325378-A Cannabinoid receptor 1 antagonists/inverse agonists and uses thereof 柯巴斯医药有限公司 2025-01-17 CN disclosed
WO-2023196556-A1 CANNABINOID RECEPTOR 1 ANTAGONISTS/INVERSE AGONISTS AND USES THEREOF CORBUS PHARMACEUTICALS, INC. (US) 2023-10-12 WO disclosed
US-11179370-B2 Cannabinoid receptor antagonists/inverse agonists useful for treating disease conditions, including metabolic disorders and cancers JENRIN DISCOVERY, LLC (US) 2021-11-23 US disclosed
US-20210023054-A1 CANNABINOID RECEPTOR ANTAGONISTS/INVERSE AGONISTS USEFUL FOR TREATING DISEASE CONDITIONS, INCLUDING METABOLIC DISORDERS AND CANCERS JENRIN DISCOVERY, INC. 2021-01-28 US disclosed
US-10617673-B2 Cannabinoid receptor antagonists/inverse agonists useful for treating metabolic disorders, including obesity and diabetes JENRIN DISCOVERY, LLC (US) 2020-04-14 US disclosed
EP-2877173-B1 CANNABINOID RECEPTOR ANTAGONISTS/INVERSE AGONISTS JENRIN DISCOVERY INC (US) 2019-11-13 EP disclosed
US-20180353478-A1 CANNABINOID RECEPTOR ANTAGONISTS/INVERSE AGONISTS USEFUL FOR TREATING METABOLIC DISORDERS, INCLUDING OBESITY AND DIABETES JENRIN DISCOVERY, LLC 2018-12-13 US disclosed
EP-2023920-A2 CANNABINOID RECEPTOR ANTAGONISTS/INVERSE AGONISTS Jenrin Discovery (US) 2009-02-18 EP disclosed
US-20090036511-A1 CANNABINOID RECEPTOR ANTAGONISTS/INVERSE AGONISTS USEFUL FOR TREATING METABOLIC DISORDERS, INCLUDING OBESITY AND DIABETES JENRIN DISCOVERY (US) 2009-02-05 US disclosed
US-7482470-B2 Cannabinoid receptor antagonists/inverse agonists useful for treating metabolic disorders, including obesity and diabetes JENRIN DISCOVERY, INC. (US) 2009-01-27 US disclosed
WO-2008144604-A1 SUBSTITUTED 2-METHYL-2-PHENOXY-N-PROPYL-PROPIONAMIDES AS CANNABINOID RECEPTOR ANTAGONISTS/INVERSE AGONISTS USEFUL FOR TREATING OBESITY JENRIN DISCOVERY (US) 2008-11-27 WO disclosed
EP-1993560-A2 CANNABINOID RECEPTOR ANTAGONISTS/INVERSE AGONISTS USEFUL FOR TREATING OBESITY Jenrin Discovery (US) 2008-11-26 EP disclosed
US-20080287505-A1 SUBSTITUTED 2-METHYL-2-PHENOXY-N-PROPYL-PROPIONAMIDES AS CANNABINOID RECEPTOR ANTAGONISTS/INVERSE AGONISTS USEFUL FOR TREATING OBESITY JENRIN DISCOVERY (US) 2008-11-20 US disclosed
WO-2007131219-A2 CANNABINOID RECEPTOR ANTAGONISTS/INVERSE AGONISTS JENRIN DISCOVERY (US) 2007-11-15 WO disclosed
US-20070259934-A1 CANNABINOID RECEPTOR ANTAGONISTS/INVERSE AGONISTS USEFUL FOR TREATING METABOLIC DISORDERS, INCLUDING OBESITY AND DIABETES JENRIN DISCOVERY (US) 2007-11-08 US disclosed
WO-2007106721-A2 CANNABINOID RECEPTOR ANTAGONISTS/INVERSE AGONISTS USEFUL FOR TREATING OBESITY JENRIN DISCOVERY (US) 2007-09-20 WO disclosed
US-20070213302-A1 pyrazoles; diabetes, cardiometabolic disorders; side effects reduction JENRIN DISCOVERY (US) 2007-09-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250248973-A1 CANNABINOID RECEPTOR 1 ANTAGONISTS/INVERSE AGONISTS AND USES THEREOF CNR1, CNR2, GPR119 MAOB 2702/4885
US-10617673-B2 Cannabinoid receptor antagonists/inverse agonists useful for treating metabolic disorders, including obesity and diabetes CNR1, CNR2, GPR119 MAOB 3683/4885
US-20070259934-A1 CANNABINOID RECEPTOR ANTAGONISTS/INVERSE AGONISTS USEFUL FOR TREATING METABOLIC DISORDERS, INCLUDING OBESITY AND DIABETES CNR2, CNR1, GPR119 MAOB 3359/4885
US-20210023054-A1 CANNABINOID RECEPTOR ANTAGONISTS/INVERSE AGONISTS USEFUL FOR TREATING DISEASE CONDITIONS, INCLUDING METABOLIC DISORDERS AND CANCERS CNR1, CNR2, GPR119 MAOB 3627/4885
US-20260092038-A1 CANNABINOID RECEPTOR 1 ANTAGONISTS/INVERSE AGONISTS AND USES THEREOF CNR1, CNR2, GPR119 MAOB 2957/4885
US-20080287505-A1 SUBSTITUTED 2-METHYL-2-PHENOXY-N-PROPYL-PROPIONAMIDES AS CANNABINOID RECEPTOR ANTAGONISTS/INVERSE AGONISTS USEFUL FOR TREATING OBESITY CNR2, CNR1, GPR119 MAOB 3421/4885
US-20090036511-A1 CANNABINOID RECEPTOR ANTAGONISTS/INVERSE AGONISTS USEFUL FOR TREATING METABOLIC DISORDERS, INCLUDING OBESITY AND DIABETES CNR2, CNR1, GPR119 MAOB 3359/4885
US-11179370-B2 Cannabinoid receptor antagonists/inverse agonists useful for treating disease conditions, including metabolic disorders and cancers CNR1, CNR2, GPR119 MAOB 3627/4885
US-20180353478-A1 CANNABINOID RECEPTOR ANTAGONISTS/INVERSE AGONISTS USEFUL FOR TREATING METABOLIC DISORDERS, INCLUDING OBESITY AND DIABETES CNR1, CNR2, GPR119 MAOB 3683/4885
US-20070213302-A1 pyrazoles; diabetes, cardiometabolic disorders; side effects reduction CNR2, CNR1, GPR119 MAOB 2220/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.