Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14715844 | 0.98 | ALDH1A1 (0.37) | THRBALDH1A1LMNAHSD17B10KDM4E | |
| SCHEMBL5704616 | 0.91 | ALDH1A1 (0.39) | THRBALDH1A1LMNAHSD17B10TDP1 | |
| SCHEMBL22801429 | 0.83 | THRB (0.39) | THRBMAPTHTTTSHR | |
| SCHEMBL5356743 | 0.82 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10TDP1HTT | |
| SCHEMBL12445294 | 0.82 | ALDH1A1 (0.46) | ALDH1A1LMNAHSD17B10TDP1HTT | |
| SCHEMBL18129217 | 0.82 | THRB (0.35) | THRB | |
| SCHEMBL14719714 | 0.81 | TSHR (0.48) | ALDH1A1LMNAHSD17B10KDM4EMAPT | |
| SCHEMBL1536970 | 0.81 | TSHR (0.40) | THRBALDH1A1TSHR | |
| SCHEMBL1536958 | 0.81 | TSHR (0.40) | THRBALDH1A1TSHR | |
| SCHEMBL1536983 | 0.81 | TSHR (0.40) | THRBALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180164630-A1 | LIQUID CRYSTAL CELL AND THREE-DIMENSIONAL STRUCTURAL LIQUID CRYSTAL CELL | FUJIFILM CORPORATION (JP) | 2018-06-14 | — | — | US | disclosed |