Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | GPR52 | Q9Y2T5 | 9/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1628157 | 0.89 | SLC7A5 (0.51) | SLC7A5GPR52CYP4F2CYP4A11KDM4E | |
| SCHEMBL290357 | 0.89 | SLC7A5 (0.51) | SLC7A5GPR52CYP4F2CYP4A11KDM4E | |
| SCHEMBL290358 | 0.89 | SLC7A5 (0.51) | SLC7A5GPR52CYP4F2CYP4A11KDM4E | |
| SCHEMBL11892098 | 0.84 | SLC7A5 (0.41) | SLC7A5GPR52CYP4F2CYP4A11PPARA | |
| SCHEMBL289958 | 0.81 | AKR1B1 (0.46) | GPR52KDM4ELMNAPPARA | |
| SCHEMBL289960 | 0.81 | AKR1B1 (0.46) | GPR52KDM4ELMNAPPARA | |
| SCHEMBL20034131 | 0.77 | PPARA (0.50) | CYP4F2CYP4A11ALDH1A1PPARA | |
| SCHEMBL22887349 | 0.74 | CYP4F2 (0.66) | SLC7A5GPR52CYP4F2CYP4A11KDM4E | |
| SCHEMBL290033 | 0.74 | SLC7A5 (0.54) | SLC7A5CYP4F2CYP4A11KDM4EALDH1A1 | |
| SCHEMBL4394735 | 0.72 | SLC7A5 (0.62) | SLC7A5CYP4F2CYP4A11KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210002202-A1 | Substituted Aromatic Compounds and Pharmaceutical Uses Thereof | PROMETIC BIOSCIENCES, INC. (CA) | 2021-01-07 | — | — | US | disclosed |
| US-10815183-B2 | Substituted aromatic compounds and pharmaceutical uses thereof | PROMETIC PHARMA SMT LIMITED (GB) | 2020-10-27 | — | — | US | disclosed |
| US-20180162799-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND PHARMACEUTICAL USES THEREOF | PROMETIC PHARMA SMT LIMITED (GB) | 2018-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180162799-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND PHARMACEUTICAL USES THEREOF | TYR, PAH, REN | SLC7A5 453/4885GPR52 1429/4885CYP4F2 74/4885 |
| US-10815183-B2 | Substituted aromatic compounds and pharmaceutical uses thereof | TYR, PAH, REN | SLC7A5 453/4885GPR52 1429/4885CYP4F2 74/4885 |
| US-20210002202-A1 | Substituted Aromatic Compounds and Pharmaceutical Uses Thereof | TYR, PAH, REN | SLC7A5 453/4885GPR52 1429/4885CYP4F2 74/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.