Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.51 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GPR52 | Q9Y2T5 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1628157 | 1.00 | SLC7A5 (0.51) | SLC7A5CYP4F2CYP4A11ALDH1A1GAA | |
| SCHEMBL290357 | 1.00 | SLC7A5 (0.51) | SLC7A5CYP4F2CYP4A11ALDH1A1GAA | |
| SCHEMBL20259161 | 0.89 | SLC7A5 (0.40) | SLC7A5CYP4F2CYP4A11ALDH1A1KDM4E | |
| SCHEMBL11892098 | 0.87 | SLC7A5 (0.41) | SLC7A5CYP4F2CYP4A11GPR52 | |
| SCHEMBL290033 | 0.85 | SLC7A5 (0.54) | SLC7A5CYP4F2CYP4A11ALDH1A1GAA | |
| SCHEMBL4394735 | 0.84 | SLC7A5 (0.62) | SLC7A5CYP4F2CYP4A11ALDH1A1GAA | |
| SCHEMBL289960 | 0.83 | AKR1B1 (0.46) | GAAKDM4ELMNAGPR52MAPT | |
| SCHEMBL289958 | 0.83 | AKR1B1 (0.46) | GAAKDM4ELMNAGPR52MAPT | |
| SCHEMBL28655132 | 0.83 | SLC7A5 (0.57) | SLC7A5CYP4F2CYP4A11ALDH1A1GAA | |
| SCHEMBL12400239 | 0.82 | SLC7A5 (0.68) | SLC7A5CYP4F2CYP4A11ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2632452-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CANCER | ProMetic BioSciences Inc. (CA) | 2013-09-04 | — | — | EP | disclosed |
| WO-2012097427-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CANCER | PROMETIC BIOSCIENCES INC. (CA) | 2012-07-26 | — | — | WO | disclosed |
| EP-2427416-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND PHARMACEUTICAL USES THEREOF | ProMetic BioSciences Inc. (CA) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010127440-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND PHARMACEUTICAL USES THEREOF | PROMETIC BIOSCIENCES INC. (CA) | 2010-11-11 | — | — | WO | disclosed |