Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 18/20 | 0.61 |
| ▸ | DYRK1A | Q13627 | 18/20 | 0.61 |
| ▸ | WNT1 | P04628 | 9/20 | 0.61 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.54 |
| ▸ | CLK2 | P49760 | 1/20 | 0.50 |
| ▸ | CLK3 | P49761 | 1/20 | 0.50 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19515815 | 0.85 | GSK3B (0.73) | GSK3BDYRK1AWNT1USP30 | |
| SCHEMBL25623359 | 0.85 | GSK3B (0.69) | GSK3BDYRK1AWNT1USP30 | |
| SCHEMBL19516204 | 0.84 | GSK3B (0.70) | GSK3BDYRK1AWNT1USP30CLK2 | |
| SCHEMBL17632071 | 0.83 | DYRK1A (0.63) | GSK3BDYRK1AWNT1USP30 | |
| SCHEMBL30004923 | 0.82 | GSK3B (0.69) | GSK3BDYRK1AWNT1USP30CLK2 | |
| SCHEMBL19515254 | 0.82 | GSK3B (0.69) | GSK3BDYRK1AWNT1USP30CLK2 | |
| SCHEMBL19515255 | 0.82 | GSK3B (0.69) | GSK3BDYRK1AWNT1USP30CLK2 | |
| SCHEMBL19544479 | 0.81 | GSK3B (0.70) | GSK3BDYRK1AWNT1USP30CLK2 | |
| SCHEMBL19515590 | 0.81 | DYRK1A (0.76) | GSK3BDYRK1AWNT1 | |
| SCHEMBL30005119 | 0.81 | DYRK1A (0.76) | GSK3BDYRK1AWNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180162852-A1 | NOVEL COMPOUNDS | MISSION THERAPEUTICS LIMITED | 2018-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180162852-A1 | NOVEL COMPOUNDS | UCHL1, UCHL3, UCHL5 | GSK3B 1950/4885DYRK1A 1587/4885WNT1 1323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.