Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22605727 | 0.84 | TP53 (0.54) | TP53ALDH1A1CYP3A4LMNATRPM8 | |
| SCHEMBL26944774 | 0.78 | TRPM8 (0.49) | TP53ALDH1A1CYP3A4LMNATRPM8 | |
| SCHEMBL23339313 | 0.77 | TP53 (0.47) | TP53ALDH1A1CYP3A4LMNATRPM8 | |
| SCHEMBL6261729 | 0.77 | TP53 (0.58) | TP53ALDH1A1CYP3A4TRPM8TSHR | |
| SCHEMBL2754185 | 0.76 | CYP3A4 (0.58) | TP53ALDH1A1CYP3A4LMNATRPM8 | |
| Hydrochloric Acid SCHEMBL27349395 | 0.75 | TP53 (0.56) | TP53ALDH1A1CYP3A4TRPM8TSHR | |
| SCHEMBL11446155 | 0.75 | ALDH1A1 (0.62) | TP53ALDH1A1CYP3A4LMNATRPM8 | |
| SCHEMBL1932869 | 0.74 | TP53 (0.42) | TP53ALDH1A1CYP3A4LMNATRPM8 | |
| SCHEMBL17899407 | 0.74 | TP53 (0.42) | TP53ALDH1A1CYP3A4LMNATRPM8 | |
| SCHEMBL17505146 | 0.74 | TRPM8 (0.57) | TP53ALDH1A1CYP3A4LMNATRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11185100-B2 | Methods for modulating taste receptors | MARS, INCORPORATED (US) | 2021-11-30 | — | — | US | disclosed |
| US-20190021380-A1 | FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME | MARS, INCORPORATED (US) | 2019-01-24 | — | — | US | disclosed |
| US-20180255813-A1 | METHODS FOR MODULATING TASTE RECEPTORS | MARS, INCORPORATED (US) | 2018-09-13 | — | — | US | disclosed |
| US-20180168208-A1 | FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME | MARS, INCORPORATED (US) | 2018-06-21 | — | — | US | disclosed |