Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 2/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1932869 | 1.00 | TP53 (0.42) | TP53ALDH1A1ESR1LMNACYP3A4 | |
| SCHEMBL23964907 | 0.85 | ESR1 (0.36) | TP53ALDH1A1ESR1LMNACYP3A4 | |
| SCHEMBL20266342 | 0.74 | TP53 (0.52) | TP53ALDH1A1ESR1LMNACYP3A4 | |
| SCHEMBL11142390 | 0.71 | TP53 (0.38) | TP53ALDH1A1PGRNPSR1ADRA2A | |
| SCHEMBL15957137 | 0.71 | ALDH1A1 (0.43) | TP53ALDH1A1ESR1LMNACYP3A4 | |
| SCHEMBL21581184 | 0.71 | CYP3A4 (0.40) | TP53ALDH1A1LMNACYP3A4TRPM8 | |
| SCHEMBL11382855 | 0.71 | ESR1 (0.40) | TP53ALDH1A1ESR1LMNACYP3A4 | |
| SCHEMBL11588386 | 0.70 | TDP1 (0.37) | TP53ALDH1A1LMNACYP3A4TRPM8 | |
| SCHEMBL22605727 | 0.69 | TP53 (0.54) | TP53ALDH1A1ESR1LMNACYP3A4 | |
| SCHEMBL4667661 | 0.69 | ALDH1A1 (0.47) | TP53ALDH1A1LMNACYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3242869-B1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF INFLAMMATION AND PAIN | CELLIX BIO PRIVATE LTD (IN) | 2021-10-27 | — | — | EP | disclosed |
| US-10343994-B2 | Compositions and methods for the treatment of inflammation and pain | KANDULA MAHESH (IN) | 2019-07-09 | — | — | US | disclosed |
| US-10227301-B2 | Compositions and methods for the treatment of inflammation and pain | CELLIX BIO PRIVATE LIMITED (IN) | 2019-03-12 | — | — | US | disclosed |
| US-20180155287-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF INFLAMMATION AND PAIN | CELLIX BIO PRIVATE LTD (IN) | 2018-06-07 | — | — | US | disclosed |
| US-20180155287-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF INFLAMMATION AND PAIN | CELLIX BIO PRIVATE LTD (IN) | 2018-06-07 | — | — | US | disclosed |
| US-9464051-B2 | Compositions and methods for the treatment of inflammation and pain | CELLIX BIO PRIVATE LIMITED (IN) | 2016-10-11 | — | — | US | disclosed |
| US-9464051-B2 | Compositions and methods for the treatment of inflammation and pain | CELLIX BIO PRIVATE LIMITED (IN) | 2016-10-11 | — | — | US | disclosed |
| US-20160207886-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF INFLAMMATION AND PAIN | CELLIX BIO PRIVATE LIMITED (IN) | 2016-07-21 | — | — | US | disclosed |
| US-20160207886-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF INFLAMMATION AND PAIN | CELLIX BIO PRIVATE LIMITED (IN) | 2016-07-21 | — | — | US | disclosed |
| WO-2016110865-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF INFLAMMATION AND PAIN | CELLIX BIO PRIVATE LIMITED (IN) | 2016-07-14 | — | — | WO | disclosed |
| US-20160194287-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF INFLAMMATION AND PAIN | KANDULA MAHESH (IN) | 2016-07-07 | — | — | US | disclosed |
| US-20160194287-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF INFLAMMATION AND PAIN | KANDULA MAHESH (IN) | 2016-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180155287-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF INFLAMMATION AND PAIN | IL1B, SI, IL4 | TP53 1990/4885ALDH1A1 2162/4885ESR1 1799/4885 |
| US-10227301-B2 | Compositions and methods for the treatment of inflammation and pain | IL1B, SI, IL4 | TP53 1990/4885ALDH1A1 2162/4885ESR1 1799/4885 |
| US-10343994-B2 | Compositions and methods for the treatment of inflammation and pain | IL1B, SI, IL4 | TP53 1990/4885ALDH1A1 2162/4885ESR1 1799/4885 |
| US-20160207886-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF INFLAMMATION AND PAIN | IL1B, SI, IL36G | TP53 1721/4885ALDH1A1 3341/4885ESR1 1864/4885 |
| US-20160194287-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF INFLAMMATION AND PAIN | IL1B, SI, IL4 | TP53 1990/4885ALDH1A1 2162/4885ESR1 1799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.