Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CCND1 | P24385 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29466252 | 0.85 | CES1 (0.47) | ALDH1A1NPC1RAB9ATSHRKMT2A | |
| SCHEMBL28068349 | 0.81 | KMT2A (0.51) | ALDH1A1RAB9AKDM4ECYP3A4CYP2C9 | |
| SCHEMBL10100516 | 0.80 | SMN1; SMN2 (0.45) | ALDH1A1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL28230697 | 0.80 | KMT2A (0.38) | ALDH1A1NPC1RAB9ATSHRKDM4E | |
| SCHEMBL30530510 | 0.79 | MEN1 (0.44) | ALDH1A1TSHRCYP2C9CYP2C19KMT2A | |
| SCHEMBL15775030 | 0.77 | HPGD (0.46) | ALDH1A1TSHRKDM4EKMT2AMEN1 | |
| SCHEMBL11606022 | 0.77 | POLB (0.47) | ALDH1A1NPC1RAB9ATSHRKMT2A | |
| SCHEMBL28231670 | 0.77 | MEN1 (0.55) | ALDH1A1NPC1RAB9AKDM4ECYP3A4 | |
| SCHEMBL15224120 | 0.75 | ALDH1A1 (0.40) | ALDH1A1NPC1RAB9ATSHRKDM4E | |
| SCHEMBL31458134 | 0.71 | CRBN (0.47) | ALDH1A1TSHRKMT2AALOX15POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018108627-A1 | USE OF SUBSTITUTED INDOLINYLMETHYL SULFONAMIDES, OR THE SALTS THEREOF FOR INCREASING THE STRESS TOLERANCE OF PLANTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-06-21 | — | — | WO | disclosed |