Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 1/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16043929 | 0.88 | LPL (0.35) | LPLLIPGP2RX7MAPK1JAK2 | |
| SCHEMBL15335320 | 0.88 | LPL (0.35) | LPLLIPGP2RX7MAPK1JAK2 | |
| SCHEMBL30486658 | 0.88 | LPL (0.35) | LPLLIPGP2RX7MAPK1JAK2 | |
| SCHEMBL1646761 | 0.80 | LPL (0.44) | LPLLIPGP2RX7MAPK1JAK2 | |
| SCHEMBL16042213 | 0.78 | LPL (0.35) | LPLLIPGJAK2BTK | |
| SCHEMBL4471407 | 0.78 | LPL (0.42) | LPLLIPGP2RX7MAPK1JAK2 | |
| SCHEMBL15056617 | 0.76 | MAPK1 (0.34) | LPLLIPGP2RX7MAPK1 | |
| SCHEMBL25395984 | 0.76 | LPL (0.41) | LPLLIPGP2RX7MAPK1JAK2 | |
| SCHEMBL17423953 | 0.74 | JAK2 (0.36) | LPLLIPGJAK2BTK | |
| SCHEMBL10159440 | 0.74 | P2RX7 (0.34) | LPLLIPGP2RX7MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011076687-A1 | PYRIDINONE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-06-30 | — | — | WO | disclosed |