Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 2/20 | 0.36 |
| ▸ | BTK | Q06187 | 2/20 | 0.36 |
| ▸ | LPL | P06858 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30955785 | 0.82 | ALDH1A1 (0.39) | JAK2BTKLPLLIPG | |
| SCHEMBL17423914 | 0.77 | LPL (0.39) | LPLLIPGROCK1 | |
| SCHEMBL30196071 | 0.76 | — | — | |
| SCHEMBL15335320 | 0.75 | LPL (0.35) | JAK2BTKLPLLIPG | |
| SCHEMBL30486658 | 0.75 | LPL (0.35) | JAK2BTKLPLLIPG | |
| SCHEMBL16043929 | 0.75 | LPL (0.35) | JAK2BTKLPLLIPGROCK1 | |
| SCHEMBL30219059 | 0.75 | LPL (0.40) | LPLLIPGROCK1 | |
| SCHEMBL2027004 | 0.74 | LPL (0.34) | JAK2BTKLPLLIPG | |
| SCHEMBL1646761 | 0.74 | LPL (0.44) | JAK2BTKLPLLIPGROCK1 | |
| SCHEMBL4471407 | 0.72 | LPL (0.42) | JAK2BTKLPLLIPGROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016007736-A1 | IMIDAZOPYRAZINES AS LSD1 INHIBITORS | INCYTE CORPORATION (US) | 2016-01-14 | — | — | WO | disclosed |
| WO-2016007731-A1 | IMIDAZOPYRIDINES AND IMIDAZOPYRAZINES AS LSD1 INHIBITORS | INCYTE CORPORATION (US) | 2016-01-14 | — | — | WO | disclosed |