SCHEMBL202739

SCHEMBL202739

CCCNC(=O)n1c(NC(=O)OCCOCC)nc2ccccc21

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.66
▸ TSHR P16473 3/20 0.66
▸ ASAH1 Q13510 4/20 0.47
▸ POLB P06746 2/20 0.40
▸ IRAK4 Q9NWZ3 1/20 0.40
▸ NPC1 O15118 2/20 0.39
▸ RAB9A P51151 2/20 0.39
▸ SMN1; SMN2 Q16637 2/20 0.39
▸ TP53 P04637 1/20 0.39
▸ KDM4E B2RXH2 3/20 0.39
▸ MEN1 O00255 1/20 0.39
▸ KMT2A Q03164 1/20 0.39
▸ USP2 O75604 1/20 0.39
▸ HPGD P15428 1/20 0.39
▸ PPARG P37231 1/20 0.39
▸ NCOA2 Q15596 1/20 0.39
▸ NCOA1 Q15788 1/20 0.39
▸ NPSR1 Q6W5P4 1/20 0.39
▸ NCOA3 Q9Y6Q9 1/20 0.39
▸ PSMD14 O00487 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL205086 0.94 TSHR (0.76) ALDH1A1TSHRASAH1POLBNPC1
SCHEMBL203352 0.91 TSHR (0.70) ALDH1A1TSHRASAH1POLBIRAK4
SCHEMBL205803 0.86 TSHR (0.87) ALDH1A1TSHRASAH1POLBIRAK4
SCHEMBL202633 0.84 ALDH1A1 (0.80) ALDH1A1TSHRASAH1POLBIRAK4
SCHEMBL7102687 0.84 TSHR (0.83) ALDH1A1TSHRASAH1POLBIRAK4
SCHEMBL28886200 0.82 TSHR (0.79) ALDH1A1TSHRASAH1POLBIRAK4
SCHEMBL5570257 0.81 TSHR (0.67) ALDH1A1TSHRASAH1POLBNPC1
SCHEMBL202740 0.80 TSHR (0.64) ALDH1A1TSHRASAH1POLBRAB9A
Benomyl SCHEMBL29379464 0.79 TSHR (1.00) ALDH1A1TSHRASAH1POLBIRAK4
Benomyl SCHEMBL8379451 0.79 TSHR (1.00) ALDH1A1TSHRASAH1POLBIRAK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 242 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3746505-B1 COMPOSITION, POLYMER COMPOSITE ARTICLE FORMED THEREWITH, AND METHOD OF PREPARING SAME DOW SILICONES CORP (US) 2024-06-26 — — EP disclosed
EP-3906245-B1 MULTIFUNCTIONAL ORGANOSILICON COMPOUND AND RELATED METHODS, COMPOUNDS, AND COMPOSITIONS DOW SILICONES CORP (US) 2024-05-29 — — EP disclosed
US-20240124709-A1 COMPOSITION, POLYMER COMPOSITE ARTICLE FORMED THEREWITH, AND METHOD OF PREPARING SAME DOW GLOBAL TECHNOLOGIES LLC 2024-04-18 — — US disclosed
EP-3645640-B1 SILICONE-POLYETHER COPOLYMER, METHOD OF PREPARING SAME, AND SEALANT COMPRISING SAME DOW SILICONES CORP (US) 2024-03-06 — — EP disclosed
US-11884821-B2 Composition, polymer composite article formed therewith, and method of preparing same DOW SILICONES CORPORATION (US) 2024-01-30 — — US disclosed
US-11820846-B2 Composition, method of preparing copolymer, and methods and end uses thereof DOW SILICONES CORPORATION (US) 2023-11-21 — — US disclosed
WO-2023215360-A1 SILICONE-POLYETHER COPOLYMER, SEALANTS COMPRISING SAME, AND RELATED METHODS DOW SILICONES CORPORATION (US) 2023-11-09 — — WO disclosed
US-11807775-B2 Silicone-organic copolymer, sealants comprising same, and related methods DOW SILICONES CORPORATION (US) 2023-11-07 — — US disclosed
CN-116874967-A Composition, polymer composite article formed therewith, and method of making the same 美国陶氏有机硅公司 2023-10-13 — — CN disclosed
US-11760841-B2 Silicone-polycarbonate copolymer, sealants comprising same, and related methods DOW SILICONES CORPORATION (US) 2023-09-19 — — US disclosed
EP-1866366-A1 ORGANOSILOXANE COMPOSITIONS Dow Corning Corporation (US) 2007-12-19 — — EP disclosed
EP-1866376-A1 ORGANOSILOXANE COMPOSITIONS Dow Corning Corporation (US) 2007-12-19 — — EP disclosed
WO-2006106359-A2 ORGANOSILOXANE COMPOSITIONS DOW CORNING CORPORATION (US) 2006-10-12 — — WO disclosed
WO-2006106360-A1 ORGANOSILOXANE COMPOSITIONS DOW CORNING CORPORATION (US) 2006-10-12 — — WO disclosed
WO-2006106362-A1 ORGANOSILOXANE COMPOSITIONS DOW CORNING CORPORATION (US) 2006-10-12 — — WO disclosed
WO-2006106095-A1 ORGANOSILOXANE COMPOSITIONS DOW CORNING CORPORATION (US) 2006-10-12 — — WO disclosed
WO-2006106361-A1 ORGANOSILOXANE COMPOSITIONS DOW CORNING CORPORATION (US) 2006-10-12 — — WO disclosed
EP-0585587-B1 Fungiresistant polyorganosiloxane composition TOSHIBA SILICONE (JP) 1997-05-21 — — EP disclosed
US-5378406-A Benzimidazolylcarbamate, pyridyl oxide zinc salt TOSHIBA SILICONE CO., LTD. (JP) 1995-01-03 — — US disclosed
EP-0585587-A1 Fungiresistant polyorganosiloxane composition TOSHIBA SILICONE CO., LTD. (JP) 1994-03-09 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11820846-B2 Composition, method of preparing copolymer, and methods and end uses thereof BRS3, OXSR1, OXER1 ALDH1A1 3354/4885TSHR 566/4885ASAH1 2942/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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