Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | ASAH1 | Q13510 | 7/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.37 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL205087 | 0.94 | TSHR (0.74) | TSHRALDH1A1ASAH1KDM4EMEN1 | |
| SCHEMBL203353 | 0.91 | TSHR (0.69) | TSHRALDH1A1ASAH1POLBKDM4E | |
| SCHEMBL202634 | 0.85 | TSHR (0.79) | TSHRALDH1A1ASAH1POLBKDM4E | |
| SCHEMBL205803 | 0.85 | TSHR (0.87) | TSHRALDH1A1ASAH1POLBKDM4E | |
| SCHEMBL202739 | 0.80 | ALDH1A1 (0.66) | TSHRALDH1A1ASAH1POLBKDM4E | |
| SCHEMBL5570257 | 0.80 | TSHR (0.67) | TSHRALDH1A1ASAH1POLBKDM4E | |
| SCHEMBL204631 | 0.79 | TSHR (0.53) | TSHRALDH1A1ASAH1POLBKDM4E | |
| SCHEMBL203352 | 0.79 | TSHR (0.70) | TSHRALDH1A1ASAH1POLBKDM4E | |
| SCHEMBL7102687 | 0.79 | TSHR (0.83) | TSHRALDH1A1ASAH1POLBKDM4E | |
| SCHEMBL28426062 | 0.79 | ALDH1A1 (0.43) | TSHRALDH1A1ASAH1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 211 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3906245-B1 | MULTIFUNCTIONAL ORGANOSILICON COMPOUND AND RELATED METHODS, COMPOUNDS, AND COMPOSITIONS | DOW SILICONES CORP (US) | 2024-05-29 | — | — | EP | disclosed |
| US-20240124709-A1 | COMPOSITION, POLYMER COMPOSITE ARTICLE FORMED THEREWITH, AND METHOD OF PREPARING SAME | DOW GLOBAL TECHNOLOGIES LLC | 2024-04-18 | — | — | US | disclosed |
| EP-3645640-B1 | SILICONE-POLYETHER COPOLYMER, METHOD OF PREPARING SAME, AND SEALANT COMPRISING SAME | DOW SILICONES CORP (US) | 2024-03-06 | — | — | EP | disclosed |
| US-11820846-B2 | Composition, method of preparing copolymer, and methods and end uses thereof | DOW SILICONES CORPORATION (US) | 2023-11-21 | — | — | US | disclosed |
| WO-2023215360-A1 | SILICONE-POLYETHER COPOLYMER, SEALANTS COMPRISING SAME, AND RELATED METHODS | DOW SILICONES CORPORATION (US) | 2023-11-09 | — | — | WO | disclosed |
| US-11807775-B2 | Silicone-organic copolymer, sealants comprising same, and related methods | DOW SILICONES CORPORATION (US) | 2023-11-07 | — | — | US | disclosed |
| CN-116874967-A | Composition, polymer composite article formed therewith, and method of making the same | 美国陶氏有机硅公司 | 2023-10-13 | — | — | CN | disclosed |
| US-11760841-B2 | Silicone-polycarbonate copolymer, sealants comprising same, and related methods | DOW SILICONES CORPORATION (US) | 2023-09-19 | — | — | US | disclosed |
| CN-111433275-B | Composition, polymer composite article formed therewith, and method of making the same | 美国陶氏有机硅公司 | 2023-07-25 | — | — | CN | disclosed |
| CN-113272364-B | Silicone-polyacrylate copolymers, sealants including silicone-polyacrylate copolymers, and related methods | 美国陶氏有机硅公司 | 2023-03-24 | — | — | CN | disclosed |
| EP-1866366-A1 | ORGANOSILOXANE COMPOSITIONS | Dow Corning Corporation (US) | 2007-12-19 | — | — | EP | disclosed |
| EP-1866376-A1 | ORGANOSILOXANE COMPOSITIONS | Dow Corning Corporation (US) | 2007-12-19 | — | — | EP | disclosed |
| WO-2006106359-A2 | ORGANOSILOXANE COMPOSITIONS | DOW CORNING CORPORATION (US) | 2006-10-12 | — | — | WO | disclosed |
| WO-2006106360-A1 | ORGANOSILOXANE COMPOSITIONS | DOW CORNING CORPORATION (US) | 2006-10-12 | — | — | WO | disclosed |
| WO-2006106362-A1 | ORGANOSILOXANE COMPOSITIONS | DOW CORNING CORPORATION (US) | 2006-10-12 | — | — | WO | disclosed |
| WO-2006106095-A1 | ORGANOSILOXANE COMPOSITIONS | DOW CORNING CORPORATION (US) | 2006-10-12 | — | — | WO | disclosed |
| WO-2006106361-A1 | ORGANOSILOXANE COMPOSITIONS | DOW CORNING CORPORATION (US) | 2006-10-12 | — | — | WO | disclosed |
| EP-0585587-B1 | Fungiresistant polyorganosiloxane composition | TOSHIBA SILICONE (JP) | 1997-05-21 | — | — | EP | disclosed |
| US-5378406-A | Benzimidazolylcarbamate, pyridyl oxide zinc salt | TOSHIBA SILICONE CO., LTD. (JP) | 1995-01-03 | — | — | US | disclosed |
| EP-0585587-A1 | Fungiresistant polyorganosiloxane composition | TOSHIBA SILICONE CO., LTD. (JP) | 1994-03-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11820846-B2 | Composition, method of preparing copolymer, and methods and end uses thereof | BRS3, OXSR1, OXER1 | TSHR 566/4885ALDH1A1 3354/4885ASAH1 2942/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.