Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 9/20 | 0.50 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.44 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.44 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.44 |
| ▸ | ACTR2 | P61160 | 1/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 7/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6076924 | 0.88 | CCR1 (0.58) | CCR1MAPK11MAPK14MAPK13MAPK12 | |
| SCHEMBL20274165 | 0.85 | PDK1 (0.46) | CCR1MAPK11MAPK14MAPK13MAPK12 | |
| SCHEMBL20274153 | 0.79 | CCR3 (0.43) | CCR3 | |
| SCHEMBL20274164 | 0.78 | KCNH2 (0.42) | CCR1 | |
| SCHEMBL2932864 | 0.78 | CCR1 (0.58) | CCR1MAPK11MAPK14MAPK13MAPK12 | |
| SCHEMBL6256307 | 0.78 | CCR1 (0.58) | CCR1MAPK11MAPK14MAPK13MAPK12 | |
| SCHEMBL5971697 | 0.78 | CCR1 (0.58) | CCR1MAPK11MAPK14MAPK13MAPK12 | |
| SCHEMBL5059509 | 0.77 | CCR1 (0.66) | CCR1MAPK11MAPK14MAPK13MAPK12 | |
| SCHEMBL5059516 | 0.77 | CCR1 (0.66) | CCR1MAPK11MAPK14MAPK13MAPK12 | |
| SCHEMBL5059507 | 0.77 | CCR1 (0.66) | CCR1MAPK11MAPK14MAPK13MAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3428162-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2021-05-05 | — | — | EP | disclosed |
| EP-2922845-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | MERIAL INC (US) | 2018-06-20 | — | — | EP | disclosed |