Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 19/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20651325 | 0.86 | ALDH1A1 (0.41) | — | |
| SCHEMBL15727593 | 0.85 | HDAC1 (0.37) | — | |
| SCHEMBL20274119 | 0.85 | HDAC1 (0.37) | — | |
| SCHEMBL20274121 | 0.79 | CCR1 (0.50) | CCR3 | |
| SCHEMBL23336086 | 0.77 | FAAH (0.57) | CCR3CYP2D6MCHR1 | |
| SCHEMBL20274208 | 0.75 | KCNH2 (0.43) | — | |
| SCHEMBL20274128 | 0.74 | PDE10A (0.40) | — | |
| SCHEMBL4586597 | 0.73 | CCR1 (0.66) | CYP2D6 | |
| SCHEMBL4586592 | 0.73 | CCR1 (0.66) | CYP2D6 | |
| SCHEMBL4588255 | 0.73 | CCR1 (0.66) | CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3428162-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2021-05-05 | — | — | EP | disclosed |
| EP-2922845-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | MERIAL INC (US) | 2018-06-20 | — | — | EP | disclosed |