Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ME2 | P23368 | 2/20 | 0.45 |
| ▸ | ME1 | P48163 | 2/20 | 0.45 |
| ▸ | ME3 | Q16798 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | GAA | P10253 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23336140 | 0.77 | AKR1C3 (0.54) | ME2ME1ME3MAPTGAA | |
| SCHEMBL15724764 | 0.73 | SIRT6 (0.42) | MAPTGAAKDM4ELMNAALDH1A1 | |
| SCHEMBL15707936 | 0.73 | SIRT6 (0.42) | MAPTGAAKDM4ELMNAALDH1A1 | |
| SCHEMBL15534608 | 0.68 | MAPT (0.56) | MAPTGAAKDM4ELMNAALDH1A1 | |
| SCHEMBL12917262 | 0.67 | ALDH1A1 (0.44) | MAPTGAAKDM4ELMNAALDH1A1 | |
| SCHEMBL15850054 | 0.67 | AKR1C3 (0.58) | ME2ME1ME3MAPTLMNA | |
| SCHEMBL12946872 | 0.67 | GRM5 (0.55) | ME2ME1ME3MAPTKDM4E | |
| SCHEMBL15850051 | 0.66 | ALDH1A1 (0.61) | ME2ME1ME3MAPTKDM4E | |
| SCHEMBL12917272 | 0.66 | AKR1C3 (0.45) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL12917263 | 0.66 | GAA (0.44) | MAPTGAAKDM4ELMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2922845-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | MERIAL INC (US) | 2018-06-20 | — | — | EP | disclosed |