Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 8/20 | 0.53 |
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ME2 | P23368 | 6/20 | 0.52 |
| ▸ | ME1 | P48163 | 6/20 | 0.52 |
| ▸ | ME3 | Q16798 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20274197 | 0.87 | AKR1C3 (0.62) | AKR1C3GAAMAPTKDM4EATM | |
| SCHEMBL20651220 | 0.84 | AKR1C3 (0.52) | AKR1C3GAAMAPTHTTNPSR1 | |
| SCHEMBL20651324 | 0.84 | AKR1C3 (0.52) | AKR1C3GAAMAPTKDM4EATM | |
| SCHEMBL20274116 | 0.84 | POLB (0.54) | AKR1C3MAPTL3MBTL1ME2ME1 | |
| SCHEMBL20274173 | 0.84 | AKR1C3 (0.68) | AKR1C3MAPTKDM4EME2ME1 | |
| SCHEMBL20274123 | 0.81 | POLB (0.55) | AKR1C3GAAMAPTKDM4EME2 | |
| SCHEMBL20274163 | 0.77 | ME2 (0.45) | GAAMAPTKDM4EATMTDP1 | |
| SCHEMBL15534608 | 0.75 | MAPT (0.56) | GAAMAPTKDM4ELMNAALDH1A1 | |
| SCHEMBL4649484 | 0.74 | HTR3A (0.69) | GAAMAPTKDM4EALDH1A1HTT | |
| SCHEMBL7723267 | 0.74 | TERT (0.55) | GAAMAPTKDM4ETDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3428162-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2021-05-05 | — | — | EP | disclosed |