Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20651340 | 0.86 | HDAC6 (0.49) | EPHX2HDAC6ALDH1A1AKR1B1TRPV1 | |
| SCHEMBL20274207 | 0.86 | HDAC6 (0.49) | EPHX2HDAC6TSHRAKR1B1NPC1 | |
| SCHEMBL20964527 | 0.84 | NPC1 (0.55) | EPHX2HDAC6LOXL2F10AKR1B1 | |
| SCHEMBL20274125 | 0.83 | AKR1B1 (0.53) | HDAC6AKR1B1TRPV1 | |
| SCHEMBL25056951 | 0.80 | LOXL2 (0.51) | HDAC6LOXL2F10TSHRAKR1B1 | |
| SCHEMBL30470713 | 0.78 | LOXL2 (0.55) | HDAC6LOXL2F10ALDH1A1DRD2 | |
| SCHEMBL24366831 | 0.78 | LOXL2 (0.55) | HDAC6LOXL2F10ALDH1A1DRD2 | |
| SCHEMBL25057150 | 0.76 | KDM4E (0.54) | HDAC6LOXL2F10ALDH1A1DRD2 | |
| SCHEMBL20274205 | 0.74 | SOS1 (0.51) | EPHX2F10AKR1B1LMNA | |
| SCHEMBL21104587 | 0.72 | LOXL2 (0.70) | HDAC6LOXL2AKR1B1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3428162-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2021-05-05 | — | — | EP | disclosed |
| EP-2922845-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | MERIAL INC (US) | 2018-06-20 | — | — | EP | disclosed |