Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.51 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.47 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | FASN | P49327 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20274161 | 0.86 | KCNH2 (0.52) | TP53KMT2AMEN1CACNA1GKCNH2 | |
| SCHEMBL20274177 | 0.83 | AKR1B1 (0.48) | AKR1B1TP53KMT2AMEN1CACNA1G | |
| SCHEMBL20274139 | 0.79 | HRH4 (0.47) | AKR1B1EPHX2KMT2AMEN1KCNH2 | |
| SCHEMBL20274216 | 0.76 | HTR2B (0.46) | EPHX2KMT2AMEN1KCNH2LMNA | |
| SCHEMBL20274140 | 0.75 | ALDH1A1 (0.48) | TP53EPHX2KMT2AKCNH2LMNA | |
| SCHEMBL20274201 | 0.74 | EPHX2 (0.52) | F10AKR1B1EPHX2LMNA | |
| SCHEMBL21104415 | 0.72 | MEN1 (0.62) | AKR1B1TP53KMT2AMEN1KCNH2 | |
| SCHEMBL23964257 | 0.71 | SOS1 (0.47) | SOS1HCRTR1HCRTR2F10TP53 | |
| SCHEMBL20274196 | 0.71 | HRH4 (0.73) | LMNA | |
| SCHEMBL9074105 | 0.70 | AKR1B1 (0.58) | AKR1B1KMT2AMEN1KCNH2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3428162-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2021-05-05 | — | — | EP | disclosed |
| EP-2922845-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | MERIAL INC (US) | 2018-06-20 | — | — | EP | disclosed |