Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 5/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20274141 | 0.80 | RAB9A (0.52) | DYRK1ALMNAMAPT | |
| SCHEMBL20274221 | 0.80 | DYRK1A (0.46) | AKR1B1DYRK1AALOX5PKMMEN1 | |
| SCHEMBL20274125 | 0.78 | AKR1B1 (0.53) | AKR1B1DYRK1AL3MBTL1TRPV1 | |
| SCHEMBL15727716 | 0.75 | AR (0.36) | AKR1B1DYRK1APKMMEN1NSD2 | |
| SCHEMBL20274215 | 0.74 | PIM1 (0.43) | HRH3L3MBTL1POLBCACNA2D1CACNA1B | |
| SCHEMBL9677093 | 0.72 | TRPV1 (0.54) | AKR1B1DYRK1AALOX5MEN1NSD2 | |
| SCHEMBL8225275 | 0.72 | DYRK1A (0.52) | AKR1B1DYRK1AALOX5MEN1NSD2 | |
| SCHEMBL9443094 | 0.72 | DYRK1A (0.54) | AKR1B1DYRK1AALOX5MEN1NSD2 | |
| SCHEMBL20964520 | 0.71 | AKR1B1 (0.52) | AKR1B1DYRK1AL3MBTL1TRPV1 | |
| SCHEMBL10516147 | 0.71 | DYRK1A (0.51) | AKR1B1DYRK1AALOX5MEN1NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3428162-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2021-05-05 | — | — | EP | disclosed |
| EP-2922845-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | MERIAL INC (US) | 2018-06-20 | — | — | EP | disclosed |