Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | RBP4 | P02753 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 6/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL604903 | 0.86 | HRH4 (0.56) | DYRK1ARBP4SMN1; SMN2HPGDRAB9A | |
| SCHEMBL20274141 | 0.84 | RAB9A (0.52) | DYRK1ARAB9A | |
| SCHEMBL28222855 | 0.84 | SCN9A (0.48) | DYRK1ARBP4SMN1; SMN2HPGDRAB9A | |
| SCHEMBL20274125 | 0.82 | AKR1B1 (0.53) | DYRK1AAKR1B1TRPV1AKR1A1 | |
| SCHEMBL20274202 | 0.80 | AKR1B1 (0.50) | DYRK1ASMN1; SMN2HPGDALOX5AKR1B1 | |
| Lithium Ion SCHEMBL31084584 | 0.75 | DYRK1A (0.56) | DYRK1AALOX5AKR1B1TRPV1MEN1 | |
| SCHEMBL3613102 | 0.75 | DYRK1A (0.56) | DYRK1AALOX5AKR1B1TRPV1MEN1 | |
| SCHEMBL3642935 | 0.75 | DYRK1A (0.58) | DYRK1AALOX5AKR1B1TRPV1MEN1 | |
| SCHEMBL3613098 | 0.73 | DYRK1A (0.57) | DYRK1AALOX5AKR1B1TRPV1MEN1 | |
| SCHEMBL20274138 | 0.71 | FAAH (0.46) | ALOX5PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2922845-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | MERIAL INC (US) | 2018-06-20 | — | — | EP | disclosed |