Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.52 |
| ▸ | NPC1 | O15118 | 7/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23657771 | 0.86 | RAB9A (0.59) | RAB9ANPC1MAPTLMNAPPARG | |
| SCHEMBL20274221 | 0.84 | DYRK1A (0.46) | RAB9ADYRK1A | |
| SCHEMBL20274125 | 0.82 | AKR1B1 (0.53) | DYRK1A | |
| SCHEMBL20274202 | 0.80 | AKR1B1 (0.50) | MAPTLMNADYRK1A | |
| SCHEMBL8514231 | 0.77 | SCN4A (0.57) | RAB9ANPC1MAPTPPARGPPARD | |
| SCHEMBL21537050 | 0.77 | MAPT (0.38) | RAB9ANPC1MAPTLMNAMAPK1 | |
| SCHEMBL3062835 | 0.76 | CNR2 (0.75) | RAB9ANPC1MAPTLMNATP53 | |
| SCHEMBL17275052 | 0.76 | DPP4 (0.38) | RAB9ANPC1MAPTLMNAMAPK1 | |
| SCHEMBL23336154 | 0.75 | CNR2 (0.59) | LMNA | |
| SCHEMBL17274982 | 0.75 | NR1H4 (0.38) | RAB9ANPC1MAPTLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3428162-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2021-05-05 | — | — | EP | disclosed |
| EP-3428162-A1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | Merial Inc. (US) | 2019-01-16 | — | — | EP | disclosed |
| EP-2922845-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | MERIAL INC (US) | 2018-06-20 | — | — | EP | disclosed |