Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA2 | P16389 | 2/20 | 0.56 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 3/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | KCNA3 | P22001 | 9/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 6/20 | 0.44 |
| ▸ | KCNA4 | P22459 | 2/20 | 0.41 |
| ▸ | KCNA1 | Q09470 | 2/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7893642 | 0.88 | KCNA2 (0.58) | KCNA2CYP1A1KDM4ECYP1A2CYP1B1 | |
| SCHEMBL31117604 | 0.82 | KCNA2 (0.57) | KCNA2CYP1A1KDM4ECYP1A2CYP1B1 | |
| SCHEMBL4188097 | 0.82 | KCNA2 (0.57) | KCNA2CYP1A1KDM4ECYP1A2CYP1B1 | |
| SCHEMBL4187228 | 0.78 | CYP3A4 (0.80) | KCNA2CYP1A1KDM4ECYP1A2CYP1B1 | |
| SCHEMBL3519659 | 0.78 | KCNA2 (0.47) | KCNA2CYP1A1KDM4ECYP1A2CYP1B1 | |
| Hydrochloric Acid SCHEMBL9222829 | 0.77 | KCNA2 (0.54) | KCNA2CYP1A1KDM4ECYP1A2CYP1B1 | |
| Bromide SCHEMBL4319744 | 0.77 | KCNA2 (0.46) | KCNA2CYP1A1KDM4ECYP1A2CYP1B1 | |
| SCHEMBL10491029 | 0.76 | MAOA (0.78) | KCNA2KDM4ECYP1A2CYP1B1CYP3A4 | |
| SCHEMBL7521625 | 0.75 | CYP3A4 (0.61) | KCNA2CYP1A1KDM4ECYP1A2CYP1B1 | |
| SCHEMBL7895128 | 0.73 | CYP3A4 (0.49) | KCNA2CYP1A1KDM4ECYP1A2CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180169433-A1 | METHODS AND SYSTEMS FOR TREATING CELL PROLIFERATION DISORDERS WITH PSORALEN DERIVATIVES | IMMUNOLIGHT, LLC (US) | 2018-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180169433-A1 | METHODS AND SYSTEMS FOR TREATING CELL PROLIFERATION DISORDERS WITH PSORALEN DERIVATIVES | NFATC1, CDK10, PDCD10 | KCNA2 4767/4885CYP1A1 1489/4885KDM4E 948/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.