Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA2 | P16389 | 2/20 | 0.58 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 2/20 | 0.46 |
| ▸ | KCNA3 | P22001 | 10/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 7/20 | 0.44 |
| ▸ | KCNA4 | P22459 | 2/20 | 0.42 |
| ▸ | KCNA1 | Q09470 | 2/20 | 0.42 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20278630 | 0.88 | KCNA2 (0.56) | KCNA2CYP1A1KDM4ECYP1A2CYP1B1 | |
| SCHEMBL4188097 | 0.86 | KCNA2 (0.57) | KCNA2CYP1A1KDM4ECYP1A2CYP1B1 | |
| SCHEMBL31117604 | 0.83 | KCNA2 (0.57) | KCNA2CYP1A1KDM4ECYP1A2CYP1B1 | |
| SCHEMBL4187228 | 0.79 | CYP3A4 (0.80) | KCNA2CYP1A1KDM4ECYP1A2CYP1B1 | |
| Hydrochloric Acid SCHEMBL9222829 | 0.78 | KCNA2 (0.54) | KCNA2CYP1A1KDM4ECYP1A2CYP1B1 | |
| SCHEMBL3446041 | 0.77 | MAOA (0.78) | KCNA2KDM4ECYP1A2CYP1B1CYP3A4 | |
| SCHEMBL3519659 | 0.77 | KCNA2 (0.47) | KCNA2CYP1A1KDM4ECYP1A2CYP1B1 | |
| Bromide SCHEMBL4319744 | 0.76 | KCNA2 (0.46) | KCNA2CYP1A1KDM4ECYP1A2CYP1B1 | |
| SCHEMBL7754086 | 0.75 | KCNA3 (0.71) | KCNA2KDM4ECYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL29503682 | 0.75 | KCNA3 (0.71) | KCNA2KDM4ECYP1A2CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998022468-A1 | PSORALEN SENSITIZERS FOR VIRAL INACTIVATION | OHIO STATE RESEARCH FOUNDATION (US) | 1998-05-28 | — | — | WO | claimed |
| US-6187572-B1 | DECONTAMINATING BLOOD AND CELL CULTURES BY MIXING WITH A CHEMICAL RADIATION SENSITIZER WHICH DOES NOT BIND TO THE MEMBRANE, FREEZING OR FREEZE-DRYING THE MIXTURE, THEN EXPOSING TO ELECTROMAGNETIC RADIATION | BAXTER INTERNATIONAL INC. | 2001-02-13 | — | — | US | disclosed |
| US-5919935-A | Psoralen sensitizers for viral inactivation | THE OHIO STATE RESEARCH FOUNDATION (US) | 1999-07-06 | — | — | US | disclosed |
| WO-1998022468-A1 | PSORALEN SENSITIZERS FOR VIRAL INACTIVATION | OHIO STATE RESEARCH FOUNDATION (US) | 1998-05-28 | — | — | WO | disclosed |
| US-5587490-A | BINDING TO A PSORALEN COMPOUND | CREDIT MANAGERS ASSOCIATION OF CALIFORNIA (US) | 1996-12-24 | — | — | US | disclosed |
| US-5418130-A | Phosphonium or ammonium halo-psoralen | CRYOPHARM CORPORATION (US) | 1995-05-23 | — | — | US | disclosed |
| WO-1995002324-A1 | METHOD OF INACTIVATION OF VIRAL AND BACTERIAL BLOOD CONTAMINANTS | CRYOPHARM CORPORATION (US) | 1995-01-26 | — | — | WO | disclosed |