SCHEMBL20280408

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20280768	1.00	ALDH1A1 (0.52)	ALDH1A1TDP1KDM4ETNFATM
	SCHEMBL20280767	0.91	ALDH1A1 (0.57)	ALDH1A1TDP1KDM4ETNFATM
	SCHEMBL6834399	0.90	ALDH1A1 (0.50)	ALDH1A1TDP1KDM4ETNFSMN1; SMN2
	SCHEMBL146521	0.89	TDP1 (0.49)	ALDH1A1TDP1KDM4EATMSMN1; SMN2
	SCHEMBL22306519	0.89	TDP1 (0.49)	ALDH1A1TDP1KDM4EATMSMN1; SMN2
	SCHEMBL14706756	0.89	KDM4E (0.53)	ALDH1A1KDM4ETNFATMSMN1; SMN2
	SCHEMBL145368	0.87	TDP1 (0.50)	ALDH1A1TDP1KDM4EATMSMN1; SMN2
	SCHEMBL21148002	0.87	TDP1 (0.43)	ALDH1A1TDP1KDM4ETSHRL3MBTL1
	SCHEMBL26920149	0.87	TDP1 (0.43)	ALDH1A1TDP1KDM4ETSHRL3MBTL1
	SCHEMBL64493	0.85	TDP1 (0.54)	ALDH1A1TDP1TNFSMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.