Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WHR1 | P49842 | 1/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | STAT6 | P42226 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.55 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28182851 | 0.88 | WHR1 (0.56) | WHR1KDM4ESTAT6NPSR1CYP1A1 | |
| SCHEMBL11865837 | 0.87 | WHR1 (0.54) | WHR1KDM4ESTAT6NPSR1ABCB1 | |
| SCHEMBL28097776 | 0.86 | DHPS (0.59) | WHR1KDM4ESTAT6NPSR1GLA | |
| SCHEMBL30227141 | 0.86 | DHPS (0.59) | WHR1KDM4ESTAT6NPSR1GLA | |
| SCHEMBL11875439 | 0.85 | PDPK1 (0.62) | WHR1KDM4ENPSR1CYP1A2ABCB1 | |
| SCHEMBL24393198 | 0.83 | WHR1 (0.73) | WHR1KDM4ESTAT6NPSR1CYP1A2 | |
| SCHEMBL22144590 | 0.83 | WHR1 (1.00) | WHR1KDM4ESTAT6NPSR1ABCB1 | |
| SCHEMBL29589069 | 0.82 | WHR1 (0.71) | WHR1KDM4ESTAT6NPSR1CYP1A2 | |
| SCHEMBL20771102 | 0.82 | WHR1 (0.71) | WHR1KDM4ESTAT6NPSR1CYP1A2 | |
| Acetic Acid SCHEMBL7268584 | 0.82 | WHR1 (0.49) | WHR1KDM4ECYP1A1CYP1A2CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106083740-B | The 4- anilinoquinazoline derivatives and preparation method of a kind of triazole containing 1,2,3- | 江苏开放大学 | 2018-05-15 | — | — | CN | claimed |
| CN-106083740-A | A kind of 4 anilinoquinazoline derivatives containing 1,2,3 triazoles and preparation method | 江苏开放大学 | 2016-11-09 | — | — | CN | claimed |
| US-11718609-B2 | Heparanase inhibitors and use thereof | Beta Therapeutics Pty Ltd (AU) | 2023-08-08 | — | — | US | disclosed |
| US-11718609-B2 | Heparanase inhibitors and use thereof | Beta Therapeutics Pty Ltd (AU) | 2023-08-08 | — | — | US | disclosed |
| US-20210130338-A1 | Heparanase Inhibitors and Use Thereof | Beta Therapeutics Pty Ltd (AU) | 2021-05-06 | — | — | US | disclosed |
| US-20200093852-A1 | Methods of Treating Ocular Disorders | Beta Therapeutics Pty Ltd (AU) | 2020-03-26 | — | — | US | disclosed |
| WO-2018107200-A1 | HEPARANASE INHIBITORS AND USE THEREOF | Beta Therapeutics Pty Ltd (AU) | 2018-06-21 | — | — | WO | disclosed |
| CN-106083740-B | The 4- anilinoquinazoline derivatives and preparation method of a kind of triazole containing 1,2,3- | 江苏开放大学 | 2018-05-15 | — | — | CN | disclosed |
| CN-106083740-A | A kind of 4 anilinoquinazoline derivatives containing 1,2,3 triazoles and preparation method | 江苏开放大学 | 2016-11-09 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200093852-A1 | Methods of Treating Ocular Disorders | ALDH1A2, HPSE, RB1 | WHR1 2926/4885KDM4E 1654/4885STAT6 1265/4885 |
| US-20210130338-A1 | Heparanase Inhibitors and Use Thereof | HPSE, HEXD, ENGASE | WHR1 4662/4885KDM4E 2390/4885STAT6 4441/4885 |
| US-11718609-B2 | Heparanase inhibitors and use thereof | HPSE, HEXD, ENGASE | WHR1 4662/4885KDM4E 2390/4885STAT6 4441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.