Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 5/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23841644 | 0.84 | DAO (0.44) | PDE2ADAOHTR2AHTR2BHTR2C | |
| SCHEMBL18733705 | 0.82 | SLC6A4 (0.39) | PDE2ADAOHTR2AHTR2BHTR2C | |
| SCHEMBL21132234 | 0.81 | PDE2A (0.41) | PDE2AHTR2AHTR2BHTR2CSIGMAR1 | |
| SCHEMBL18896392 | 0.81 | IDO1 (0.49) | PDE2AHTR2AHTR2BHTR2CSIGMAR1 | |
| SCHEMBL25916270 | 0.78 | NR3C1 (0.49) | SLC6A4 | |
| SCHEMBL12603811 | 0.77 | DAO (0.51) | PDE2ADAOMAPTRXRARXRB | |
| SCHEMBL18294991 | 0.76 | DAO (0.46) | PDE2ADAOHTR2AHTR2BHTR2C | |
| SCHEMBL2654304 | 0.75 | RXRA (0.47) | MC4RMAPTRXRARXRBRXRG | |
| SCHEMBL16950937 | 0.74 | DAO (0.53) | PDE2ADAOSIGMAR1RXRARXRB | |
| SCHEMBL13003550 | 0.74 | ALDH1A1 (0.46) | PDE2AHTR2AHTR2BHTR2CSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018109642-A1 | N-ARYL PYRAZOLES AS NRF2 REGULATORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2018-06-21 | — | — | WO | disclosed |