SCHEMBL202833

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL203683	0.88	POLB (0.43)	POLBL3MBTL1ATP4AATP4BPPARD
	SCHEMBL203280	0.88	L3MBTL1 (0.59)	POLBL3MBTL1ATP4AATP4BALDH1A1
	SCHEMBL201521	0.86	PPARD (0.49)	POLBL3MBTL1ALDH1A1NPC1RAB9A
	SCHEMBL19471118	0.84	L3MBTL1 (0.49)	POLBL3MBTL1ALDH1A1NPC1RAB9A
	SCHEMBL201522	0.84	NPC1 (0.42)	NPC1RAB9ASMN1; SMN2PPARDPPARA
	SCHEMBL204593	0.83	L3MBTL1 (0.46)	POLBL3MBTL1NPC1RAB9AHTT
	SCHEMBL201115	0.83	PPARD (0.44)	L3MBTL1PPARDPPARAMAPT
	SCHEMBL2707296	0.82	RAB9A (0.54)	POLBL3MBTL1ALDH1A1NPC1RAB9A
	SCHEMBL204423	0.82	L3MBTL1 (0.45)	POLBL3MBTL1ALDH1A1NPC1RAB9A
	SCHEMBL2705816	0.82	L3MBTL1 (0.53)	POLBL3MBTL1ATP4AATP4BALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.