Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.71 |
| ▸ | ATM | Q13315 | 1/20 | 0.71 |
| ▸ | PIM1 | P11309 | 1/20 | 0.67 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.61 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.59 |
| ▸ | WNT3A | P56704 | 1/20 | 0.59 |
| ▸ | AHR | P35869 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28129599 | 0.89 | GPR84 (0.79) | GPR84ALDH1A1PBRM1ATMPIM1 | |
| SCHEMBL10645520 | 0.89 | GPR84 (0.79) | GPR84ALDH1A1PBRM1ATMPIM1 | |
| SCHEMBL9208355 | 0.89 | GPR84 (0.79) | GPR84ALDH1A1PBRM1ATMPIM1 | |
| SCHEMBL3279652 | 0.88 | GPR84 (0.79) | GPR84ALDH1A1PBRM1ATMPIM1 | |
| SCHEMBL29988308 | 0.88 | GPR84 (0.79) | GPR84ALDH1A1PBRM1ATMPIM1 | |
| SCHEMBL31651424 | 0.88 | GPR84 (0.77) | GPR84ALDH1A1PBRM1ATMPIM1 | |
| SCHEMBL6251507 | 0.88 | GPR84 (0.77) | GPR84ALDH1A1PBRM1ATMPIM1 | |
| SCHEMBL8530849 | 0.88 | GPR84 (0.77) | GPR84ALDH1A1PBRM1ATMPIM1 | |
| SCHEMBL11167081 | 0.88 | GPR84 (0.77) | GPR84ALDH1A1PBRM1ATMPIM1 | |
| SCHEMBL31651417 | 0.88 | GPR84 (0.77) | GPR84ALDH1A1PBRM1ATMPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 530 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119143773-B | Preparation method of indolone spiro isochromanone derivative | 山东第二医科大学 | 2025-01-28 | — | — | CN | claimed |
| CN-119143773-A | Preparation method of indolone spiro isochromanone derivative | 山东第二医科大学 | 2024-12-17 | — | — | CN | claimed |
| WO-2024217520-A1 | INDOLONE FLT3 PROTEIN DEGRADATION AGENT, AND PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 南京中医药大学 | 2024-10-24 | — | — | WO | claimed |
| CN-105198861-B | 6- acyl group -1,2,4- triazine -3,5- derovatives and herbicide | FMC公司 | 2019-11-22 | — | — | CN | claimed |
| CN-109879789-A | A kind of preparation method of substituted indole ketones derivant | 贵州医科大学 | 2019-06-14 | — | — | CN | claimed |
| CN-104784699-B | Folate receptor binding ligand-drug conjugates | 博瑞生物医药（苏州）股份有限公司 | 2019-05-03 | — | — | CN | claimed |
| CN-109574907-A | A kind of indole ketone compound and the preparation method and application thereof | 天津科技大学 | 2019-04-05 | — | — | CN | claimed |
| CN-109422673-A | A method of synthesis indole ketone compound containing iodine | 浙江工业大学 | 2019-03-05 | — | — | CN | claimed |
| CN-109053691-A | A kind of synthetic method of bis- substituted chiral indole ketone compound of 3,3- | 深圳市众康动保科技有限公司 | 2018-12-21 | — | — | CN | claimed |
| CN-108822017-A | New indole ketone compound and its preparation method and medicinal usage | 中国医学科学院药物研究所 | 2018-11-16 | — | — | CN | claimed |
| CN-102491979-A | 1-hydroxyethyl-5-substituted indolone derivative and preparation method and application thereof | UNIV TIANJIN SCIENCE & TECH | 2012-06-13 | — | — | CN | claimed |
| US-8003073-B2 | Dehydrogenation of hydrogen carrier; heat provided by reverse selective oxidation of carrier; endotyhermic reactions | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2011-08-23 | — | — | US | claimed |
| CN-102146095-A | Pyrrole indolone compounds and preparation method and use thereof | NANTONG BORUI BIOMEDICAL CO LTD | 2011-08-10 | — | — | CN | claimed |
| WO-2009005872-A2 | AUTOTHERMAL HYDROGEN STORAGE AND DELIVERY SYSTEMS | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2009-01-08 | — | — | WO | claimed |
| US-20080260630-A1 | Autothermal Hydrogen Storage and Delivery Systems | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2008-10-23 | — | — | US | claimed |
| CN-100371325-C | Indenoindole ketone kind compound, its preparation method and use | SHANGHAI INST PHARM INDUSTRY (CN) | 2008-02-27 | — | — | CN | claimed |
| CN-1724520-A | One class indenoindole ketone compounds, Preparation Method And The Use | SHANGHAI INST PHARM INDUSTRY (CN) | 2006-01-25 | — | — | CN | claimed |
| CN-1425635-A | Method for producing biologically fermented active organic fertilizer by using organic wasters and its device | ZHANG WEIMIN (CN) | 2003-06-25 | — | — | CN | claimed |
| CN-1345724-A | Indolylpiperidine compound and preparation process and use thereof | SHANGHAI PHARMACEUTICAL INST C (CN) | 2002-04-24 | — | — | CN | claimed |
| US-5741801-A | 5-HT4 receptor antagonist | SMITHKLINE BEECHAM PLC (GB) | 1998-04-21 | — | — | US | claimed |