SCHEMBL8530849

SCHEMBL8530849

O=C(c1cccc2ccccc12)c1c[nH]c2ccccc12

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.77
ALDH1A1 P00352 3/20 0.57
KMT2A Q03164 3/20 0.57
MEN1 O00255 2/20 0.57
MAPT P10636 2/20 0.57
MAPK1 P28482 2/20 0.57
TP53 P04637 2/20 0.57
KDM4E B2RXH2 1/20 0.57
LMNA P02545 1/20 0.57
HPGD P15428 1/20 0.57
CDC25B P30305 1/20 0.57
PBRM1 Q86U86 1/20 0.57
ATM Q13315 1/20 0.57
AHR P35869 2/20 0.56
NPSR1 Q6W5P4 2/20 0.55
PIM1 P11309 1/20 0.55
HTT P42858 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
NR4A2 P43354 3/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29489280 1.00 GPR84 (0.77) GPR84ALDH1A1KMT2AMEN1MAPT
SCHEMBL2028344 0.88 GPR84 (1.00) GPR84ALDH1A1KMT2AMEN1MAPK1
SCHEMBL9640753 0.87 CDC25B (0.57) GPR84ALDH1A1KMT2AMEN1MAPT
SCHEMBL6327424 0.86 GPR84 (0.60) GPR84ALDH1A1KMT2AMEN1MAPT
SCHEMBL11984941 0.85 GPR84 (0.55) GPR84ALDH1A1KMT2AMEN1MAPT
SCHEMBL29808478 0.84 F7 (0.60) GPR84KMT2AMEN1MAPTCDC25B
SCHEMBL15558983 0.84 GPR84 (0.54) GPR84ALDH1A1KMT2AMEN1MAPT
SCHEMBL22955917 0.84 GPR84 (0.54) GPR84ALDH1A1KMT2AMEN1MAPT
SCHEMBL14111893 0.83 CDC25B (0.54) GPR84ALDH1A1KMT2AMEN1MAPT
SCHEMBL6402031 0.83 SMN1; SMN2 (0.63) GPR84KMT2AMEN1MAPTTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10175258-B2 Detection of synthetic cannabinoids RANDOX LABORATORIES LIMITED (GB) 2019-01-08 US claimed
CN-104402992-B A kind of synthetic method synthesizing hemp antigen and the application for synthesizing hemp antigen 杭州安旭科技有限公司 2018-09-18 CN claimed
US-20150118763-A1 DETECTION OF SYNTHETIC CANNABINOIDS RANDOX LABORATORIES LIMITED (GB) 2015-04-30 US claimed
CN-104402992-A Synthetic method for synthesizing cannabis sativa antigen and application of synthesized cannabis sativa antigen HANGZHOU ASSURE TECHNOLOGY CO LTD 2015-03-11 CN claimed
EP-2487155-B1 Detection of Synthetic Cannabinoids RANDOX LAB LTD (GB) 2015-01-21 EP claimed
US-8906633-B2 Detection of synthetic cannabinoids RANDOX LABORATORIES LIMITED (GB) 2014-12-09 US claimed
CN-102838525-A Synthesis method of 1-amyl-3-(1naphthoyl) indole JIANGSU HAOHUA FINE CHEMICAL CO LTD 2012-12-26 CN claimed
US-20120208213-A1 Detection of Synthetic Cannabinoids RANDOX LABORATORIES LIMITED (GB) 2012-08-16 US claimed
EP-2487155-A1 Detection of Synthetic Cannabinoids Randox Laboratories Ltd. (GB) 2012-08-15 EP claimed
US-20250195409-A1 METHODS FOR IMPROVING CUTANEOUS PERMEATION OF CANNABINOIDS AND FATTY ACID AMIDES Ananda Scientific, Inc. (US) 2025-06-19 US disclosed
EP-4110325-A1 TRANSDERMAL AND/OR TOPICAL PHARMACEUTICAL FORMULATIONS COMPRISING CANNABIDIOL AND/OR TETRAHYDROCANNABINOL FOR THE TREATMENT OF CHRONIC PAIN Pike Therapeutics, Inc. (CA) 2023-01-04 EP disclosed
WO-2022217147-A1 METHODS FOR IMPROVING CUTANEOUS PERMEATION OF CANNABINOIDS AND FATTY ACID AMIDES ROSENFELD MARK J (US) 2022-10-13 WO disclosed
EP-3958856-A1 COMPOSITIONS AND METHODS FOR USE OF CANNABINOIDS FOR NEUROPROTECTION Inmed Pharmaceuticals Inc. (CA) 2022-03-02 EP disclosed
US-10968206-B2 Cannabinergic nitrate esters and related analogs NORTHEASTERN UNIVERSITY (US) 2021-04-06 US disclosed
EP-2487155-A1 Detection of Synthetic Cannabinoids Randox Laboratories Ltd. (GB) 2012-08-15 EP disclosed
US-5817651-A ANALGESICS, RHEUMATIC DISEASES, ANTIINFLAMMATORY AGENTS SANOFI (FR) 1998-10-06 US disclosed
US-5607933-A METHODS FOR TREATMENT OF GLAUCOMA AND FOR RELIEF OF PAIN AND RHEUMATIC AND INFLAMMATORY CONDITIONS BY ADMINISTERING THE INDOLES; N-HETERYL IS 2-PIPERAZINYL STERLING WINTHROP INC. (US) 1997-03-04 US disclosed
US-5324737-A Analgesics, antirheumatic and antiinflammatory agents, glaucoma STERLING WINTHROP INC. (US) 1994-06-28 US disclosed
US-5068234-A Analgesics, rheumatic diseases, antiinflammatory agents or antiglaucoma STERLING DRUG INC. (US) 1991-11-26 US disclosed
EP-0444451-A2 3-Arylcarbonyl-1H-indoles useful as therapeutic agents STERLING WINTHROP INC. (US) 1991-09-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150118763-A1 DETECTION OF SYNTHETIC CANNABINOIDS CNR2, CNR1, FAAH GPR84 64/4885ALDH1A1 4246/4885KMT2A 2187/4885
US-10968206-B2 Cannabinergic nitrate esters and related analogs CNR2, CNR1, CHRNB3 GPR84 315/4885ALDH1A1 1850/4885KMT2A 4178/4885
US-20250195409-A1 METHODS FOR IMPROVING CUTANEOUS PERMEATION OF CANNABINOIDS AND FATTY ACID AMIDES CNR2, CNR1, FAAH GPR84 106/4885ALDH1A1 1320/4885KMT2A 2718/4885
US-20120208213-A1 Detection of Synthetic Cannabinoids CNR2, CNR1, FAAH GPR84 64/4885ALDH1A1 4246/4885KMT2A 2187/4885
US-10175258-B2 Detection of synthetic cannabinoids CNR2, CNR1, FAAH GPR84 64/4885ALDH1A1 4246/4885KMT2A 2187/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.