Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | RGS12 | O14924 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9268820 | 0.81 | SMN1; SMN2 (0.37) | ALDH1A1HTR2ACYP2C19CYP3A4ALOX15 | |
| SCHEMBL15787495 | 0.80 | CHRNA7 (0.37) | ALDH1A1KMT2AMEN1LMNATDP1 | |
| SCHEMBL15787496 | 0.80 | CHRNA7 (0.37) | ALDH1A1KMT2AMEN1LMNATDP1 | |
| SCHEMBL4841608 | 0.78 | TAAR1 (0.40) | ALDH1A1HTR2ACYP2C19CYP3A4ALOX15 | |
| SCHEMBL897649 | 0.77 | KDM4E (0.38) | ALDH1A1CYP2C19CYP3A4ALOX15TSHR | |
| Ammonia Solution, Strong SCHEMBL27951261 | 0.77 | HDAC1 (0.39) | ALDH1A1CYP2C19CYP3A4ALOX15TSHR | |
| SCHEMBL1444029 | 0.77 | AOC3 (0.42) | ALDH1A1HTR2ACYP2C19CYP3A4ALOX15 | |
| SCHEMBL9631266 | 0.77 | CYP3A4 (0.35) | ALDH1A1HTR2ACYP2C19CYP3A4ALOX15 | |
| SCHEMBL9416672 | 0.77 | SMN1; SMN2 (0.35) | ALDH1A1CYP2C19CYP3A4ALOX15TSHR | |
| SCHEMBL9631211 | 0.77 | ALDH1A1 (0.39) | ALDH1A1CYP2C19CYP3A4ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118271624-A | Amphiphilic block copolymer and preparation method and application thereof | 广州孔确基因科技有限公司 | 2024-07-02 | — | — | CN | claimed |
| CN-118271624-A | Amphiphilic block copolymer and preparation method and application thereof | 广州孔确基因科技有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-115243780-A | Filter material | 东丽株式会社 | 2022-10-25 | — | — | CN | disclosed |
| EP-2166074-B1 | CLEANING AGENT | ESPO CHEMICALS CORP (JP) | 2013-03-20 | — | — | EP | disclosed |
| US-7956026-B2 | Cleaning agent | ESPO CHEMICALS CORP. (JP) | 2011-06-07 | — | — | US | disclosed |
| US-20100216686-A1 | CLEANING AGENT | ESPO CHEMICALS CORPORATION (JP) | 2010-08-26 | — | — | US | disclosed |
| EP-2166074-A1 | CLEANING AGENT | Espo Chemicals, Corp. (JP) | 2010-03-24 | — | — | EP | disclosed |
| US-7342007-B2 | Lactams and uses thereof | ASTRAZENECA AB (SE) | 2008-03-11 | — | — | US | disclosed |
| US-7342007-B2 | Lactams and uses thereof | ASTRAZENECA AB (SE) | 2008-03-11 | — | — | US | disclosed |
| US-7342007-B2 | Lactams and uses thereof | ASTRAZENECA AB (SE) | 2008-03-11 | — | — | US | disclosed |
| US-20060183732-A1 | Novel lactams and uses thereof | ASTRAZENECA AB (SE) | 2006-08-17 | — | — | US | disclosed |
| EP-1636196-A1 | NOVEL LACTAMS AND USES THEREOF | AstraZeneca AB (SE) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004080983-A1 | NOVEL LACTAMS AND USES THEREOF | ASTRAZENECA AB (SE) | 2004-09-23 | — | — | WO | disclosed |
| WO-2004080983-A1 | NOVEL LACTAMS AND USES THEREOF | ASTRAZENECA AB (SE) | 2004-09-23 | — | — | WO | disclosed |
| CN-1007727-B | PROCESS FOR THE PREPARATION OF TETRAHYDRONAPHTALINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 1990-04-25 | — | — | CN | disclosed |
| US-4680310-A | HYPOTENSIVE AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1987-07-14 | — | — | US | disclosed |
| CN-85107496-A | The method for preparing tetrahydronaphthalenderivatives derivatives | — | 1986-07-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183732-A1 | Novel lactams and uses thereof | BACE1, BACE2, APP | ALDH1A1 2419/4885HTR2A 4121/4885CYP2C19 841/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.