Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 6/20 | 0.42 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL342906 | 0.98 | AOC3 (0.41) | AOC3DPP4F2CTSDHTR2A | |
| SCHEMBL9268820 | 0.81 | SMN1; SMN2 (0.37) | DPP4F2HTR2ATAAR1SMN1; SMN2 | |
| SCHEMBL9416672 | 0.77 | SMN1; SMN2 (0.35) | DPP4F2SMN1; SMN2CYP2C19ALDH1A1 | |
| SCHEMBL897649 | 0.77 | KDM4E (0.38) | DPP4F2SMN1; SMN2CYP2C19ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL27951261 | 0.77 | HDAC1 (0.39) | SMN1; SMN2CYP2C19ALDH1A1KDM4ECYP3A4 | |
| SCHEMBL9631266 | 0.77 | CYP3A4 (0.35) | DPP4F2HTR2ATAAR1SMN1; SMN2 | |
| SCHEMBL2028407 | 0.77 | ALDH1A1 (0.46) | HTR2ATAAR1SMN1; SMN2CYP2C19ALDH1A1 | |
| SCHEMBL9631211 | 0.77 | ALDH1A1 (0.39) | DPP4F2SMN1; SMN2CYP2C19ALDH1A1 | |
| SCHEMBL5440741 | 0.76 | TDP1 (0.43) | CTSDSMN1; SMN2CYP2C19ALDH1A1KDM4E | |
| SCHEMBL13296205 | 0.76 | RAB9A (0.41) | DPP4F2SMN1; SMN2CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4919916-A | Treatment of neurotransmitter-linked drug abuse | GOLWYN DANIEL H (US) | 1990-04-24 | — | — | US | claimed |
| US-4786653-A | Treatment of neurotransmitter-linked drug abuse | GOLWYN DANIEL H (US) | 1988-11-22 | — | — | US | claimed |
| US-20240190837-A1 | CARBAZOLE-CONTAINING AMIDES, CARBAMATES, AND UREAS AS CRYPTOCHROME MODULATORS | SYCHRONICITY PHARMA INC (US) | 2024-06-13 | — | — | US | disclosed |
| US-20220411399-A1 | CARBAZOLE-CONTAINING AMIDES, CARBAMATES, AND UREAS AS CRYPTOCHROME MODULATORS | SYCHRONICITY PHARMA INC (US) | 2022-12-29 | — | — | US | disclosed |
| CN-110003172-B | Carbazole-containing amides, carbamates, and ureas as cryptochrome modulators | 同步制药公司 | 2022-04-01 | — | — | CN | disclosed |
| EP-3939971-A1 | CARBAZOLE-CONTAINING AMIDES, CARBAMATES, AND UREAS AS CRYPTOCHROME MODULATORS | Synchronicity Pharma, Inc. (US) | 2022-01-19 | — | — | EP | disclosed |
| CN-107674071-B | Carbazole-containing sulfonamides as cryptochrome modulators | 同步制药公司 | 2021-12-31 | — | — | CN | disclosed |
| US-20210171495-A1 | CARBAZOLE-CONTAINING AMIDES, CARBAMATES, AND UREAS AS CRYPTOCHROME MODULATORS | Synchronicity Pharma, Inc. | 2021-06-10 | — | — | US | disclosed |
| EP-3129366-B1 | CARBAZOLE-CONTAINING AMIDES, CARBAMATES, AND UREAS AS CRYPTOCHROME MODULATORS | SYNCHRONICITY PHARMA INC (US) | 2021-06-09 | — | — | EP | disclosed |
| EP-3777846-A1 | VAP-1 INHIBITORS FOR TREATING PAIN | BenevolentAI Cambridge Limited (GB) | 2021-02-17 | — | — | EP | disclosed |
| US-10759777-B2 | Carbazole-containing amides, carbamates, and ureas as cryptochrome modulators | Synchronicity Pharma, Inc. (US) | 2020-09-01 | — | — | US | disclosed |
| US-20030181516-A1 | Substance with sedative effect | TECHNOLOGY COMMERCIALIZATION CORP. | 2003-09-25 | — | — | US | disclosed |
| US-5428063-A | For treating or preventing fatty infiltration, the first stage of cirrhosis | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 1995-06-27 | — | — | US | disclosed |
| US-5219858-A | Method and compositions for effecting withdrawal from drug dependency | PARNELL PHARMACEUTICALS, INC. (US) | 1993-06-15 | — | — | US | disclosed |
| US-5051426-A | Method for effecting withdrawal from drug dependency | PARNELL PHARMACEUTICALS, INC. (US) | 1991-09-24 | — | — | US | disclosed |
| US-5017602-A | Antidotes for nerve gas, herbicides, insecticides | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1991-05-21 | — | — | US | disclosed |
| US-4919916-A | Treatment of neurotransmitter-linked drug abuse | GOLWYN DANIEL H (US) | 1990-04-24 | — | — | US | disclosed |
| US-4919916-A | Treatment of neurotransmitter-linked drug abuse | GOLWYN DANIEL H (US) | 1990-04-24 | — | — | US | disclosed |
| US-4786653-A | Treatment of neurotransmitter-linked drug abuse | GOLWYN DANIEL H (US) | 1988-11-22 | — | — | US | disclosed |
| US-4786653-A | Treatment of neurotransmitter-linked drug abuse | GOLWYN DANIEL H (US) | 1988-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210171495-A1 | CARBAZOLE-CONTAINING AMIDES, CARBAMATES, AND UREAS AS CRYPTOCHROME MODULATORS | CRY1, CRY2, HCCS | AOC3 3171/4885DPP4 611/4885F2 635/4885 |
| US-10759777-B2 | Carbazole-containing amides, carbamates, and ureas as cryptochrome modulators | CRY1, CRY2, HCCS | AOC3 3171/4885DPP4 611/4885F2 635/4885 |
| US-20220411399-A1 | CARBAZOLE-CONTAINING AMIDES, CARBAMATES, AND UREAS AS CRYPTOCHROME MODULATORS | CRY1, CRY2, HCCS | AOC3 3171/4885DPP4 611/4885F2 635/4885 |
| US-20240190837-A1 | CARBAZOLE-CONTAINING AMIDES, CARBAMATES, AND UREAS AS CRYPTOCHROME MODULATORS | CRY1, CRY2, HCCS | AOC3 3171/4885DPP4 611/4885F2 635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.