Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9268820 | 0.81 | SMN1; SMN2 (0.37) | SMN1; SMN2CYP2C19ALDH1A1ALOX15CYP3A4 | |
| SCHEMBL9631211 | 0.77 | ALDH1A1 (0.39) | SMN1; SMN2CYP2C19ALDH1A1ALOX15CYP3A4 | |
| SCHEMBL2028407 | 0.77 | ALDH1A1 (0.46) | SMN1; SMN2CYP2C19ALDH1A1ALOX15CYP3A4 | |
| Ammonia Solution, Strong SCHEMBL27951261 | 0.77 | HDAC1 (0.39) | SMN1; SMN2CYP2C19ALDH1A1ALOX15CYP3A4 | |
| SCHEMBL897649 | 0.77 | KDM4E (0.38) | SMN1; SMN2CYP2C19ALDH1A1ALOX15CYP3A4 | |
| SCHEMBL9631266 | 0.77 | CYP3A4 (0.35) | SMN1; SMN2CYP2C19ALDH1A1ALOX15CYP3A4 | |
| SCHEMBL1444029 | 0.77 | AOC3 (0.42) | SMN1; SMN2CYP2C19ALDH1A1ALOX15CYP3A4 | |
| SCHEMBL4445401 | 0.76 | MTOR (0.52) | SMN1; SMN2CYP2C19ALDH1A1ALOX15CYP3A4 | |
| SCHEMBL5440741 | 0.76 | TDP1 (0.43) | SMN1; SMN2CYP2C19ALDH1A1ALOX15CYP3A4 | |
| SCHEMBL13296205 | 0.76 | RAB9A (0.41) | SMN1; SMN2CYP2C19ALDH1A1ALOX15CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5312984-A | Amidation of vinyl chloride with dimethylamine using a supported palladium catalyst | THE B. F. GOODRICH COMPANY (US) | 1994-05-17 | — | — | US | disclosed |
| US-5159113-A | Vinyl chloride reacted with carbon monoxide and amine | THE B. F. GOODRICH COMPANY (US) | 1992-10-27 | — | — | US | disclosed |