Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 20/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20286601 | 0.92 | RORC (0.65) | RORC | |
| SCHEMBL20286603 | 0.90 | RORC (0.65) | RORCCYP2C9CYP2C19 | |
| SCHEMBL18275355 | 0.89 | RORC (0.81) | RORCCYP2C9CYP2C19 | |
| SCHEMBL20286609 | 0.86 | RORC (0.60) | RORCCYP2C9CYP2C19 | |
| SCHEMBL14754201 | 0.86 | RORC (0.72) | RORCCYP2C9CYP2C19 | |
| SCHEMBL14746651 | 0.82 | RORC (0.70) | RORCCYP2C9CYP2C19 | |
| SCHEMBL18294347 | 0.82 | RORC (0.52) | RORCCYP2C9CYP2C19 | |
| SCHEMBL14744485 | 0.82 | RORC (0.72) | RORCCYP2C9CYP2C19 | |
| SCHEMBL18275302 | 0.81 | RORC (0.82) | RORCCYP2C9CYP2C19 | |
| SCHEMBL14744113 | 0.80 | RORC (0.81) | RORCCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180170863-A1 | ROR GAMMA (RORY) MODULATORS | LEAD PHARMA HOLDING B.V. (NL) | 2018-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180170863-A1 | ROR GAMMA (RORY) MODULATORS | RORB, RORA, RORC | RORC 3/4885CYP2C9 490/4885CYP2C19 930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.