SCHEMBL2029205

SCHEMBL2029205

NC(=O)C[C@@H](CO)NC(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.37
KMT2A Q03164 1/20 0.37
CYP2C19 P33261 1/20 0.36
KIF11 P52732 4/20 0.36
HTT P42858 1/20 0.35
CYP3A4 P08684 1/20 0.35
MAPK1 P28482 1/20 0.35
ALDH1A1 P00352 3/20 0.35
RAB9A P51151 1/20 0.35
KDM4E B2RXH2 1/20 0.35
KCNN4 O15554 4/20 0.34
CYP2D6 P10635 3/20 0.34
CYP1A2 P05177 2/20 0.34
PKM P14618 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
ITGB2 P05107 1/20 0.33
ICAM1 P05362 1/20 0.33
ITGAL P20701 1/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2032169 1.00 MAPT (0.37) MAPTKMT2ACYP2C19KIF11HTT
SCHEMBL29557422 0.87 CYP2C19 (0.38) MAPTKMT2ACYP2C19KIF11HTT
SCHEMBL25657681 0.87 CYP2C19 (0.38) MAPTCYP2C19KIF11CYP3A4MAPK1
SCHEMBL7479981 0.82 KCNN4 (0.43) MAPTKMT2ACYP2C19KIF11CYP3A4
SCHEMBL569600 0.80 KIF11 (0.44) KIF11CYP3A4MAPK1KDM4EKCNN4
SCHEMBL569601 0.80 KIF11 (0.44) KIF11CYP3A4MAPK1KDM4EKCNN4
SCHEMBL14559281 0.80 KIF11 (0.44) KIF11CYP3A4MAPK1KDM4EKCNN4
SCHEMBL28694554 0.79 ALDH1A1 (0.48) MAPTKMT2ACYP2C19KIF11ALDH1A1
SCHEMBL2021383 0.79 ALDH1A1 (0.48) MAPTKMT2ACYP2C19KIF11ALDH1A1
SCHEMBL2021385 0.79 ALDH1A1 (0.48) MAPTKMT2ACYP2C19KIF11ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10633630-B2 Acceleration of Mycobacterium growth ST GEORGE'S HOSPITAL MEDICAL SCHOOL (GB) 2020-04-28 US disclosed
EP-3158053-B1 ACCELERATION OF MYCOBACTERIUM GROWTH ST GEORGES HOSPITAL MEDICAL SCHOOL (GB) 2019-03-13 EP disclosed
US-9707282-B2 Small cationic antimicrobial peptides THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2017-07-18 US disclosed
US-20170121672-A1 ACCELERATION OF MYCOBACTERIUM GROWTH ST GEORGE'S HOSPITAL MEDICAL SCHOOL (GB) 2017-05-04 US disclosed
US-20150315240-A1 SMALL CATIONIC ANTIMICROBIAL PEPTIDES THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2015-11-05 US disclosed
US-9017656-B2 Small cationic antimicrobial peptides THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2015-04-28 US disclosed
EP-2061886-B1 Small cationic immunomodulatory peptides UNIV BRITISH COLUMBIA (CA) 2014-05-07 EP disclosed
US-20130266597-A1 Small Cationic Antimicrobial Peptides THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2013-10-10 US disclosed
US-8343475-B2 Small cationic antimicrobial peptides THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2013-01-01 US disclosed
US-20110236429-A1 Small Cationic Antimicrobial Peptides THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2011-09-29 US disclosed
US-20110150917-A1 Small Cationic Antimicrobial Peptides THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2011-06-23 US disclosed
EP-2061886-A1 SMALL CATIONIC ANTIMICROBIAL PEPTIDES The University of British Columbia (CA) 2009-05-27 EP disclosed
WO-2008022444-A1 SMALL CATIONIC ANTIMICROBIAL PEPTIDES THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2008-02-28 WO disclosed